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854883-46-8

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854883-46-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 854883-46-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,4,8,8 and 3 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 854883-46:
(8*8)+(7*5)+(6*4)+(5*8)+(4*8)+(3*3)+(2*4)+(1*6)=218
218 % 10 = 8
So 854883-46-8 is a valid CAS Registry Number.

854883-46-8Relevant articles and documents

Design and synthesis of novel 2-phenylaminopyrimidine (PAP) derivatives and their antiproliferative effects in human chronic myeloid leukemia cells

Chang, Sheng,Yin, Shi-Liang,Wang, Jian,Jing, Yong-Kui,Dong, Jin-Hua

experimental part, p. 4166 - 4179 (2009/12/28)

A series of novel 2-phenylaminopyrimidine (PAP) derivatives structurally related to STI-571 were designed and synthesized. The abilities of these compounds to inhibit proliferation were tested in human chronic myeloid leukemia K562 cells. (E)-3-(2-bromophenyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2- ylamino)phenyl]acrylamide( 12d) was the most effective cell growth inhibitor and was 3-fold more potent than STI-571.

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