85589-35-1

Basic information

• Product Name: 2-Methylmandelic acid
• Synonyms: 2-Methylmandelic acid
• CAS NO: 85589-35-1
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• Mol File: 85589-35-1.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methylmandelic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylmandelic acid(85589-35-1)
• EPA Substance Registry System: 2-Methylmandelic acid(85589-35-1)

Safety Data

• Hazardous Substances Data: 85589-35-1(Hazardous Substances Data)

Upstream product

• 67-66-3 chloroform 
• 529-20-4 2-methylphenyl aldehyde 
• 932-31-0 ortho-tolylmagnesium bromide 
• 100-51-6 benzyl alcohol 
• 161236-66-4 2-Benzyloxymethyl-4,4-dimethyl-4,5-dihydro-oxazole 
• 118-90-1 ortho-methylbenzoic acid 
• 85589-34-0 2-hydroxy-2-(2-methylphenyl)acetonitrile 
• 75-25-2 Bromoform 
• 161236-74-4 (4,4-Dimethyl-4,5-dihydro-oxazol-2-yl)-o-tolyl-methanol 
• 62281-72-5 ethyl hydroxy(2-methylphenyl)acetate 

Downstream Products

• 62281-72-5 ethyl hydroxy(2-methylphenyl)acetate 
• 1619932-82-9 2-oxo-N-phenyl-2-(2-tolyl)acetamide 
• 1619933-00-4 ethyl (E)-3-[(2S,3R,4R)-4-hydroxy-5-oxo-1,2-diphenyl-4-(2-tolyl)pyrrolidin-3-yl]acrylate 
• 149922-98-5 2-(2-methylphenyl)glyoxyloyl chloride 
• 1236046-48-2 (2-(pyridin-2’-yl)phenyl)(o-tolyl)methanone 
• 1359987-66-8 methyl 2-acetoxy-2-(2-methylphenyl)acetate 
• 104383-24-6 methyl 2-hydroxy-2-(o-tolyl)acetate 
• 1584127-64-9 (S)-(+)-methyl 2-acetoxy-2-(2-methylphenyl)acetate 
• 887641-46-5 C₁₆H₁₆O₃ 
• 1355328-12-9 C₂₈H₃₁FN₂O₃S 

Relevant articles and documents

Silica sulfuric acid as a highly efficient catalyst for the synthesis of diarylacetic acids

ABSTRACT: An efficient heterogeneous method for the synthesis of diarylacetic acids was developed utilizing silica sulfuric acid as a catalyst. The reaction is highly efficient with a small amount of catalyst for the combination of a variety of electron-n

Relationships between the racemic structures of substituted mandelic acids containing 8- and 10-membered hydrogen bonded dimer rings

The structures of 27 monosubstituted mandelic acids, including several of their polymorphs, plus unsubstituted mandelic acid itself (two polymorphs) are investigated for structural similarity. The results, presented pictorially as a structural relationship plot, show that rather more structures are built up from the carboxyl-chain hydroxyl hydrogen bonded dimer than from the conventional carboxylic acid dimer. The results show how all the structures are related and, based on the two types of dimer, the degree of similarity that they possess. Some structures with Z′ > 1 contain both sorts of dimers and there are many examples of isostructural sets within the structures so far determined. We also present an example where analysing similarity in related families of structures highlights a structure that should be present and which has indeed then proceeded to be synthesised and determined.

Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30

By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed.