85614-43-3 Usage
Description
Methyl 5-allyl-3-methoxysalicylate is an organic compound that appears as a white to pale yellow powder. It is a versatile reactant in the synthesis of various chemical compounds.
Uses
Used in Pharmaceutical Industry:
Methyl 5-allyl-3-methoxysalicylate is used as a reactant in the synthesis of Fallypride (F101115), a selective dopamine D2 receptor antagonist used in medical imaging and research.
Used in Chemical Synthesis:
Methyl 5-allyl-3-methoxysalicylate is used as a reactant for the synthesis of enterobactin scaffolds, which are part of the siderophore family and play a role in iron uptake in bacteria.
Used in Organic Chemistry:
Methyl 5-allyl-3-methoxysalicylate is used as a reactant for the synthesis of allylic amines, which are important intermediates in organic chemistry and have applications in the production of pharmaceuticals, agrochemicals, and other specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 85614-43-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,6,1 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 85614-43:
(7*8)+(6*5)+(5*6)+(4*1)+(3*4)+(2*4)+(1*3)=143
143 % 10 = 3
So 85614-43-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O4/c1-4-5-8-6-9(12(14)16-3)11(13)10(7-8)15-2/h4,6-7,13H,1,5H2,2-3H3
85614-43-3Relevant articles and documents
Choleretic drug alibendol preparation method
-
Paragraph 0017-0018; 0020-0021, (2019/06/30)
The invention belongs to the field of drug synthesis, and provides an alibendol preparation method, which comprises: selecting 2-hydroxy-3-methoxybenzaldehyde as a raw material, selecting an efficientoxidative esterification catalyst, carrying out one-step oxidative esterification to obtain methyl 2-hydroxy-3-methoxybenzoate, carrying out a reaction on the methyl 2-hydroxy-3-methoxybenzoate and allyl bromide under the action of an alkali to generate methyl 2-allyloxy-3-methoxybenzoate, carrying out a para Claisen rearrangement reaction on the methyl 2-allyloxy-3-methoxybenzoate at a high temperature to obtain methyl 2-hydroxy-3-methoxy-5-allylbenzoate, and carrying out an aminolysis reaction in ethanolamine to generate alibendol. Compared with the traditional synthetic process, the new process of the present invention has characteristics of simple synthesis steps, convenient post-treatment and good product quality, and is suitable for industrial production.
