85624-04-0Relevant articles and documents
Pyrolysis of azetidinone derivatives: A versatile route towards electron-rich alkenes, C-1 allylation and/or homologation of aldehydes
Al-Hamdan, Nouf S.,Habib, Osama M.,Ibrahim, Yehia A.,Al-Awadi, Nouria A.,El-Dusouqui, Osman M. E.
, p. 21023 - 21031 (2014/06/09)
Pyrolysis of β-lactams and β-thiolactams led essentially to stereoselective synthesis of the high energy electron-rich Z-alkenes. Extension of this methodology to the pyrolysis of 3-allyloxy derivatives gave a simple direct route to the synthetically important 4-pentenal. These pyrolytic transformations convert aldehydes to aryloxyalkenes (a protected homologation) and 4-pentenal (a C-1 allylation and homologation). The starting 3-aryloxy and 3-allyloxy-β-lactams were synthesized by the standard Staudinger ketene-imine [2 + 2] cycloaddition. The corresponding β-thiolactams have readily been obtained in good yields by thiation of β-lactams with Lawesson's reagent. This journal is the Partner Organisations 2014.
SCELETIUM (AIZOACEAE) ALKALOIDS: SHORT TOTAL SYNTHESIS OF RACEMIC O-METHYLJOUBERTAMINE BY THE ARYLACETONITRILE ROUTE
Sanchez, I. H.,Lemini, C.,Hernandez, C.,Larraza, M. I.,Flores, H. J.,et al.
, p. 43 - 51 (2007/10/02)
-
