85643-19-2

Basic information

• Product Name: CURCULIGOSIDE
• Synonyms: CURCULIGOSIDE;[5-Hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]methyl-2,6-dimethoxybenzoate;CurculigosideA;β-D-Glucopyranoside,2-[[(2,6-diMethoxybenzoyl)oxy]Methyl]-4-hydroxyphenyl;Curculigoside, 98%, from Curculigo orchioides Gaertn.
• CAS NO: 85643-19-2
• Molecular Formula: C22H26O11
• Molecular Weight: 466.44
• Product Categories: Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 85643-19-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 158-160 °C(Solv: methanol (67-56-1))
• Boiling Point: 734.9 °C at 760 mmHg
• Flash Point: 253.8 °C
• Appearance: /
• Density: 1.45 g/cm³
• Vapor Pressure: 1.13E-22mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: -20°C Freezer
• Solubility: Methanol (Slightly)
• PKA: 9.70±0.20(Predicted)
• CAS DataBase Reference: CURCULIGOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: CURCULIGOSIDE(85643-19-2)
• EPA Substance Registry System: CURCULIGOSIDE(85643-19-2)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 85643-19-2(Hazardous Substances Data)

Usage

Description

Curculigoside is a natural steroidal saponin glycoside that can be extracted from the tubers of the Curculigo orchioides plant. It has been found to possess various biological activities, including neuroprotective, angiogenic, and osteogenic properties.

Uses

Used in Pharmaceutical Industry:
Curculigoside is used as a neuroprotective agent for protecting the brain against injury. It may aid in the treatment of neurological disorders and conditions associated with brain damage.
Used in Regenerative Medicine:
Curculigoside is used as an osteogenic agent to improve the osteogenesis of human amniotic fluid-derived stem cells. This property can be utilized in bone tissue engineering and regenerative medicine for the treatment of bone defects and disorders.
Used in Angiogenesis Research:
Curculigoside is used as an angiogenic agent to induce angiogenesis through the Vcam-1/Egr-3/CREB/VEGF signal pathway. This property can be applied in the development of therapeutic strategies for various conditions, such as wound healing, tissue regeneration, and cardiovascular diseases.

InChI:InChI=1/C22H26O11/c1-29-14-4-3-5-15(30-2)17(14)21(28)31-10-11-8-12(24)6-7-13(11)32-22-20(27)19(26)18(25)16(9-23)33-22/h3-8,16,18-20,22-27H,9-10H2,1-2H3/t16-,18-,19+,20-,22-/m1/s1