85679-03-4

Basic information

• Product Name: 1-Phenylnaphthalene-2-carboxylic acid
• Synonyms: 1-Phenylnaphthalene-2-carboxylic acid
• CAS NO: 85679-03-4
• Molecular Formula: C₁₇H₁₂O₂
• Molecular Weight: 248.27598
• Mol File: 85679-03-4.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Phenylnaphthalene-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenylnaphthalene-2-carboxylic acid(85679-03-4)
• EPA Substance Registry System: 1-Phenylnaphthalene-2-carboxylic acid(85679-03-4)

Safety Data

• Hazardous Substances Data: 85679-03-4(Hazardous Substances Data)

Usage

Naphthalene derivative

A compound derived from naphthalene, which is a polycyclic aromatic hydrocarbon consisting of two fused benzene rings.

Carboxylic acid group

A functional group (-COOH) present in the compound, contributing to its acidic properties.

Phenyl group

A benzene ring attached to another carbon chain or ring, contributing to the structure and properties of the compound.

Pharmaceutical industry use

Utilized in the synthesis of various drugs, including anti-inflammatory and anti-tumor agents.

Antimicrobial properties

Potential ability to inhibit or kill microorganisms, such as bacteria and fungi.

Antioxidant properties

Potential ability to neutralize free radicals, which can cause cellular damage and contribute to aging and diseases.

Organic light emitting diodes (OLEDs)

Investigated for its role in the development of OLEDs due to its fluorescent properties, which can be useful in display technologies.

Applications in medicine, materials science, and electronics

The compound's diverse properties make it suitable for various applications across these fields, including drug development, material design, and electronic device manufacturing.

Upstream product

• 85678-97-3 4,4-dimethyl-2-(1-phenylnaphthalen-2-yl)-4,5-dihydrooxazole 
• 98-80-6 phenylboronic acid 
• 31790-95-1 methyl 1-phenyl-2-naphthalenecarboxylate 
• 948-03-8 1-hydroxy-naphthalene-2-carboxylic acid methyl ester 
• 5123-13-7 5,5-dimethyl-2-phenyl-1,3,2-dioxaborinane 
• 75472-75-2 (E)-N-((naphthalen-6-yl)methylene)benzenamine 
• 125454-79-7 1-phenylnaphthalene-2-carbaldehyde 
• 574-97-0 1-fluoronaphthalene-2-carboxylic acid 
• 100-58-3 phenylmagnesium bromide 
• 591-51-5 phenyllithium 
• 883-21-6 1-methoxy-2-naphthoic acid 
• 108-86-1 bromobenzene 
• 78265-10-8 2-<2-(1-methoxynaphthyl)>-4,4-dimethyl-Δ²-oxazoline 
• 51439-63-5 1-methoxy-2-naphthoyl chloride 

Downstream Products

• 205-12-9 benzo[c]fluorene 
• 161950-64-7 2-hydroxymethyl-1-phenylnaphthalene 
• 59310-32-6 1-(3-phenylnaphthalen-2-yl)ethanone 

Relevant articles and documents

Visible-Light-Induced Arene C(sp 2)-H Lactonization Promoted by DDQ and tert -Butyl Nitrite

A visible-light photocatalytic aerobic oxidative lactonization of arene C(sp 2)-H bonds proceeds in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and tert -butyl nitrite (TBN). Under the optimized conditions, a range of 2-arylbenzoic acids is converted into the corresponding benzocoumarin derivatives in moderate to excellent yields. This method is characterized by its atom economy, mild reaction conditions, the use of a green oxidant and metal-free catalysis.

Synthesis of substituted helicenes by Ir-catalyzed annulative coupling of biarylcarboxylic acid chlorides with alkynes

A series of substituted [4] and [5]helicenes were synthesized in moderate to good yields by an Ir-catalyzed annulative coupling of biarylcarboxylic acid chlorides with internal alkynes, which involves facile C-H bond cleavage and decarbonylation. The double annulative coupling of 1, 1′:5′, 1″-ternaphthalene- 2, 2″-dicarboxylic acid dichloride with 4-octyne was also accomplished to give rise to an S-shaped double helicene. Unexpectedly, a π-extended benzofluoranthene-merged [5]- helicene was constructed through the annulative coupling and the successive C(aryl)-C(aryl) bond forming reaction when 1, 1′:4′, 1″-ternaphthalene-2, 2″-dicarboxylic acid dichloride was employed as the substrate. The crystal structure and the optical properties of the latter unique product were also investigated.

Ruthenium(0)-Catalyzed C-H Arylation of Aromatic Imines under Neutral Conditions: Access to Biaryl Aldehydes

The first ruthenium(0)-catalyzed C-H bond arylation of aromatic imines with arylboronates under neutral conditions is reported. This versatile method provides rapid access to a wide range of biaryl aldehydes that are difficult to assemble using traditional methods with high atom economy. A new hydrogen acceptor for Ru(0) arylation has been identified. This atom-economical strategy has potential for an array of direct applications in Ru(0)-catalyzed C-H bond arylations using removable directing groups. An indole synthesis by a sequential one-pot, multiple C-H activation protocol is reported.