857288-56-3

Basic information

• Product Name: N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropylamine hydrobromide
• Synonyms: N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropylamine hydrobromide
• CAS NO: 857288-56-3
• Molecular Weight: 420.433
• Mol File: 857288-56-3.mol
• Article Data: 2

Chemical Properties

• Density: 1.2 at 20℃
• CAS DataBase Reference: N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropylamine hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropylamine hydrobromide(857288-56-3)
• EPA Substance Registry System: N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropylamine hydrobromide(857288-56-3)

Safety Data

• Hazardous Substances Data: 857288-56-3(Hazardous Substances Data)

Upstream product

• 124935-88-2 N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine 

Downstream Products

• 124935-88-2 N,N-diisopropyl-3-(2-methoxy-5-methylphenyl)-3-phenylpropan-1-amine 

Relevant articles and documents

METHOD OF OBTAINING 3,3-DIPHENYLPROPYLAMINES

The invention relates to a method of obtaining 3,3-diphenylpropylamines (I), wherein R1 is H, alkyl, haloalkyl or alkoxyalkyl, R2 is alkyl, alkoxy, halogen, NO2, CN, CHO, which may be free or protected, CH2OH or COOR6, and R3 and R4 are selected independently from H and alkyl or together with the nitrogen to which they are bound form a ring having 3 to 7 members. The inventive method consists in reacting a propylenephenylamine and a disubstituted aromatic hydrocarbon and, if necessary, separating the desired enantiomer or the mixture of enantiomers, and/or converting the compound (I) into a salt. Compounds (I) are muscarinic receptor antagonists which can be used in the treatment of urinary incontinence and other symptoms of urinary bladder hyperactivity. Said compounds include tolterodine.