857652-06-3

Basic information

• Product Name: 2-Bromomethyl-3-methoxy-benzoic acid
• Synonyms: 2-Bromomethyl-3-methoxy-benzoic acid
• CAS NO: 857652-06-3
• Molecular Formula: C9H9BrO3
• Molecular Weight: 245.073
• Mol File: 857652-06-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Bromomethyl-3-methoxy-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromomethyl-3-methoxy-benzoic acid(857652-06-3)
• EPA Substance Registry System: 2-Bromomethyl-3-methoxy-benzoic acid(857652-06-3)

Safety Data

• Hazardous Substances Data: 857652-06-3(Hazardous Substances Data)

Upstream product

• 55289-06-0 3-methoxy-2-methylbenzoic acid 

Downstream Products

• 1221486-61-8 2-[2-(3-chlorophenyl)-vinyl]-3-methoxybenzoic acid 
• 1221486-03-8 R-8-(2-aminophenylamino)-1-(2,3-dihydroxypropoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one 
• 1221486-02-7 S-8-(2-aminophenylamino)-1-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one 
• 1221485-99-9 8-(2-aminophenylamino)-1-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one 
• 1221486-05-0 8-(2,4-difluorophenylamino)-1-(2-morpholin-4-yl-ethoxy)-10,11-dihydrodibenzo-[a,d]cyclohepten-5-one 
• 1221486-01-6 R-8-(2,4-difluorphenylamino)-1-(2,3-dihydroxypropoxy)-10,11-dihydrodibenzo-[a,d]cyclohepten-5-one 
• 1221486-04-9 8-(2,4-difluorophenylamino)-1-(tetrahydropyran-4-yloxy)-10,11-dihydro-dibenzo-[a,d]cyclohepten-5-one 
• 1221485-97-7 8-(2,4-difluorophenylamino)-1-hydroxy-10,11-dihydro-dibenzo[a,d]cyclohepten-5-one 
• 1221485-98-8 8-(2,4-difluorophenylamino)-1-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one 
• 1221486-62-9 2-[2-(3-chlorophenyl)-ethyl]-3-methoxybenzoic acid 
• 1221486-00-5 S-8-(2,4-difluorophenylamino)-1-(2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-10,11-dihydrodibenzo[a,d]cyclohepten-5-one 
• 857651-74-2 2-bromomethyl-3-methoxy-benzaldehyde 
• 857652-07-4 (2-bromomethyl-3-methoxy-phenyl)-methanol 

Relevant articles and documents

DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS

The present invention relates to compounds of the formula I wherein R1, R2, R3, R4, X and Y have the meanings given in the description. The compounds have an action which is immunomodulating and inhibits or regulates the release of IL-1β and/or TNF-α. The

The total synthesis of coleophomones B, C, and D

Members of the coleophomone family of natural products all possess several intriguing and challenging architectural features, as well as exhibit unusual biological activity. They, therefore, constitute attractive targets for synthesis. In this Article, we describe the total synthesis of coleophomones B (2), C (3), and D (4). The highly strained and congested 11-membered macrocycle of coleophomones B (2) and C (3) was constructed using an impressive olefin metathesis reaction. Furthermore, both of the requisite geometric isomers of the Δ within the macrocycle could be accessed from a common precursor, facilitating a divergence that lent the coleophomone B (2)/C (3) synthesis an unusually high degree of efficiency. The synthesis of coleophomone D (4) confirmed that it exists as a dynamic mixture of isomeric forms with a different aromatic substitution pattern from the other family members.