857934-86-2

Basic information

• Product Name: phenyl-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol
• CAS NO: 857934-86-2
• Molecular Weight: 310.201
• Mol File: 857934-86-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: phenyl-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol(857934-86-2)
• EPA Substance Registry System: phenyl-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol(857934-86-2)

Safety Data

• Hazardous Substances Data: 857934-86-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 73852-88-7 2-(4-iodophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 106-37-6 1.4-dibromobenzene 
• 61676-62-8 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1195-66-0 2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 5467-74-3 4-Bromophenylboronic acid 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 68716-49-4 p-bromophenylboronic acid pinacol ester 

Relevant articles and documents

A synthetic approach to dimetalated arenes using flow microreactors and the switchable application to chemoselective cross-coupling reactions

In spite of their potential utility, the chemistry of dimetalated arenes is still in its infancy because they are extremely difficult to synthesize. We report a novel method of synthesizing arenes bearing a boryl group and a metallic substituent, such as boryl, silyl, stannyl, or zincyl groups, in an integrated flow microreactor based on the generation and reactions of aryllithiums bearing a trialkyl borate moiety. The bimetallic arenes showed a remarkable chemoselectivity in palladium-catalyzed cross-coupling reactions. The selectivity was switched by the selection of the metal species that constitutes the dimetalated arenes as well as appropriate catalysts.

Preparation and selective reactions of mixed bimetallic aromatic and heteroaromatic boron-magnesium reagents

(Chemical Equation Presented) It's all in the mix: The magnesiation of iodoaryl and iodoheteroaryl boronic esters with iPrMgCl·LiCl leads to mixed bimetallic compounds, which react with a variety of electrophiles to provide highly functionalized boronic e