85826-32-0

Basic information

• Product Name: 5-ALLYL-2-METHYL-4,6-PYRIMIDINEDIOL
• Synonyms: 5-ALLYL-2-METHYL-4,6-PYRIMIDINEDIOL;5-allyl-6-hydroxy-2-methylpyrimidin-4(3H)-one
• CAS NO: 85826-32-0
• Molecular Formula: C₈H₁₀N₂O₂
• Molecular Weight: 166.18
• Mol File: 85826-32-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 319°C at 760 mmHg
• Flash Point: 146.8°C
• Appearance: /
• Density: 1.245g/cm³
• Vapor Pressure: 0.000186mmHg at 25°C
• Refractive Index: 1.588
• CAS DataBase Reference: 5-ALLYL-2-METHYL-4,6-PYRIMIDINEDIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ALLYL-2-METHYL-4,6-PYRIMIDINEDIOL(85826-32-0)
• EPA Substance Registry System: 5-ALLYL-2-METHYL-4,6-PYRIMIDINEDIOL(85826-32-0)

Safety Data

• Hazardous Substances Data: 85826-32-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H10N2O2/c1-3-4-6-7(11)9-5(2)10-8(6)12/h3H,1,4H2,2H3,(H2,9,10,11,12)

Upstream product

• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 124-42-5 acetamidine hydrochloride 

Downstream Products

• 1001397-56-3 1-methylethyl 4-({7-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)-1-piperidinecarboxylate 
• 1001397-53-0 1,1-dimethylethyl 4-({7-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)-1-piperidinecarboxylate 
• 1001397-52-9 4-chloro-7-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 
• 1001397-48-3 6-chloro-N-[2-fluoro-4-(methylsulfonyl)phenyl]-2-methyl-5-(2-propen-1-yl)-4-pyrimidinamine 
• 85826-33-1 5-Allyl-2-methyl-4,6-dichloropyrimidine 
• 85826-41-1 Benzyl-[6-chloro-5-(2,3-dibromo-propyl)-2-methyl-pyrimidin-4-yl]-amine 
• 85826-37-5 (5-Allyl-6-chloro-2-methyl-pyrimidin-4-yl)-benzyl-amine 
• 85826-40-0 2-[6-Chloro-5-(2,3-dibromo-propyl)-2-methyl-pyrimidin-4-ylamino]-ethanol 
• 85826-39-7 [6-Chloro-5-(2,3-dibromo-propyl)-2-methyl-pyrimidin-4-yl]-methyl-amine 
• 85826-36-4 2-(5-Allyl-6-chloro-2-methyl-pyrimidin-4-ylamino)-ethanol 
• 85826-38-6 4-Amino-5-(2',3'-dibromo-1'-propyl)-2-methyl-6-chloropyrimidine 
• 85826-35-3 (5-Allyl-6-chloro-2-methyl-pyrimidin-4-yl)-methyl-amine 
• 85826-34-2 5-Allyl-4-amino-2-methyl-6-chloropyrimidine 

Relevant articles and documents

Discovery of 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines as orally available g protein-coupled receptor 119 agonists

GPR119 is a 7-transmembrane receptor that is expressed in the enteroendocrine cells in the intestine and in the islets of Langerhans in the pancreas. Indolines and 6,7-dihydro-5H-pyrrolo[2,3-a]pyrimidines were discovered as G protein-coupled receptor 119

CONDENSED N-HETEROCYCLIC COMPOUNDS AND THEIR USE AS CRF RECEPTOR ANTAGONISTS

The present invention provides compounds of formula (I) including stereoisomers, prodrugs and pharmaceutically acceptable salts or solvates thereof (Formula (I)) wherein the dashed line may represent a double bond; R is aryl or heteroaryl, each of which m