85864-86-4

Basic information

• Product Name: 8-Iodonaphthalene-1-carboxaldehyde
• Synonyms: 8-Iodonaphthalene-1-carboxaldehyde
• CAS NO: 85864-86-4
• Molecular Formula: C₁₁H₇IO
• Molecular Weight: 282.07715
• Mol File: 85864-86-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 81-82 °C
• Boiling Point: 378.5±15.0 °C(Predicted)
• Appearance: /
• Density: 1.793±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 8-Iodonaphthalene-1-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Iodonaphthalene-1-carboxaldehyde(85864-86-4)
• EPA Substance Registry System: 8-Iodonaphthalene-1-carboxaldehyde(85864-86-4)

Safety Data

• Hazardous Substances Data: 85864-86-4(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 104489-30-7 (8-iodo-1-naphthyl)lithium 
• 479-27-6 naphthalene-1,8-diamine 
• 1730-04-7 1,8-diiodonaphthalene 
• 85864-84-2 (8-iodonaphthalen-1-yl)methanol 

Downstream Products

• 232-89-3 3H-benzindazole 
• 85864-88-6 8-iodo-1-naphthaldehyde p-tosylhydrazone 

Relevant articles and documents

Synthesis and properties of 9-alkyl- and 9-arylcyclopenta[a]phenalenes

(equation presented) Two strategies for the synthesis of cyclopenta[a]phenalenes are described. NMR, X-ray diffraction, and cyclic voltammetry studies of simple alkyl- and aryl-substituted derivatives are reported for the first time.

Studies in Acyl C-H activation via aryl and alkyl to acyl "through space" migration of palladium

Examples of the 1,4-migration of a palladium moiety in aryl- and alkylpalladium intermediates to the acyl position of an aldehyde or formamide have been observed. The resulting acylpalladium intermediate can undergo ester or carbamate formation by reaction with an alcohol; decarbonylation, followed by β hydride elimination to an alkene; reaction with an organomercurial to form an ester; or alkene insertion. Deuterium-labeling studies have been used to confirm the palladium migration mechanism.