858838-09-2

Basic information

• Product Name: 2-cyclohexyl-5-methyl-1H-pyrazol-3(2H)-one
• Synonyms: 2-cyclohexyl-5-methyl-1H-pyrazol-3(2H)-one
• CAS NO: 858838-09-2
• Molecular Weight: 180.25
• Mol File: 858838-09-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-cyclohexyl-5-methyl-1H-pyrazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclohexyl-5-methyl-1H-pyrazol-3(2H)-one(858838-09-2)
• EPA Substance Registry System: 2-cyclohexyl-5-methyl-1H-pyrazol-3(2H)-one(858838-09-2)

Safety Data

• Hazardous Substances Data: 858838-09-2(Hazardous Substances Data)

Upstream product

• 6498-34-6 cyclohexylhydrazine 
• 141-97-9 ethyl acetoacetate 
• 24214-73-1 cyclohexylhydrazine hydrochloride 
• 105-45-3 acetoacetic acid methyl ester 
• 19735-89-8 3-methyl-1-phenylpyrazolin-5(4H)-one 

Relevant articles and documents

CARBOXAMIDE DERIVATIVES

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or co-crystal thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Pyrazolone methylamino piperidine derivatives as novel CCR3 antagonists

The discovery and optimization of a novel class of potent CCR3 antagonists is described. Details of synthesis and SAR are given together with some ADME properties of selected compounds. An optimal balance between activities, physicochemical properties, and in vitro metabolic stability was reached by the proper choice of substituents.