859518-35-7

Basic information

• Product Name: 4-N-Boc-2-cyanopiperidine
• Synonyms: 4-N-Boc-2-cyanopiperidine;4-Boc-2-cyanopiperidine;4-N-Boc-2-cyanopiperazine;1-Piperazinecarboxylic acid, 3-cyano-, 1,1-diMethylethyl ester;1-Boc-3-cyanopiperazine;tert-Butyl 3-cyanopiperazine-1-carboxylate;3-Cyano-1-piperazinecarboxylic acid 1,1-dimethylethyl ester;tert-Butyl-2-cyanpiperidin-4-carboxylat
• CAS NO: 859518-35-7
• Molecular Formula: C₁₀H₁₇N₃O₂
• Molecular Weight: 210.27282
• Mol File: 859518-35-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 343℃
• Flash Point: 161℃
• Appearance: /
• Density: 1.12
• Vapor Pressure: 0.000271mmHg at 25°C
• Refractive Index: 1.48
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.88±0.40(Predicted)
• CAS DataBase Reference: 4-N-Boc-2-cyanopiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-N-Boc-2-cyanopiperidine(859518-35-7)
• EPA Substance Registry System: 4-N-Boc-2-cyanopiperidine(859518-35-7)

Safety Data

• Hazardous Substances Data: 859518-35-7(Hazardous Substances Data)

Usage

General Description

4-N-Boc-2-cyanopiperidine is a specialized chemical compound used predominantly in the pharmaceutical industry. Its primary function is as an intermediate in the synthesis of various drugs. 4-N-Boc-2-cyanopiperidine belongs to the category of organic compounds known as piperidines, characterized by a piperidine ring, a six-membered ring with one nitrogen atom and five carbon atoms. It is further characterized by the presence of a cyano functional group (-CN) and tert-butoxycarbonyl (Boc) protecting group, commonly used in organic synthesis. The use of such chemicals requires careful handling due to their reactivity and potential health effects.

InChI:InChI=1/C11H18N2O2/c1-11(2,3)15-10(14)8-4-5-13-9(6-8)7-12/h8-9,13H,4-6H2,1-3H3

Upstream product

• 187589-36-2 piperazine-2-carbonitrile 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 187589-36-2 piperazine-2-carbonitrile 
• 1369237-75-1 tert-butyl 3-(aminomethyl)-4-methylpiperazine-1-carboxylate 

Relevant articles and documents

Antibodies to quetiapine haptens and use thereof

Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.

HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS

The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from quetiapine. The invention also relates to conjugates of a quetiapine hapten and a protein.