860374-18-1

Basic information

• Product Name: 2-diazo-N-(4-methoxy-phenyl)-malonamic acid ethyl ester
• Synonyms: 2-diazo-N-(4-methoxy-phenyl)-malonamic acid ethyl ester
• CAS NO: 860374-18-1
• Molecular Weight: 263.253
• Mol File: 860374-18-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-diazo-N-(4-methoxy-phenyl)-malonamic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-diazo-N-(4-methoxy-phenyl)-malonamic acid ethyl ester(860374-18-1)
• EPA Substance Registry System: 2-diazo-N-(4-methoxy-phenyl)-malonamic acid ethyl ester(860374-18-1)

Safety Data

• Hazardous Substances Data: 860374-18-1(Hazardous Substances Data)

Upstream product

• 996-82-7 sodium diethylmalonate 
• 2101-87-3 p-methoxy-phenylazide 
• 99-35-4 1,3,5-trinitrobenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 75-05-8 acetonitrile 
• 7601-90-3 perchloric acid 
• 623-73-4 diazoacetic acid ethyl ester 
• 124-38-9 carbon dioxide 
• 104-94-9 4-methoxy-aniline 

Relevant articles and documents

Direct Carboxylation of the Diazo Group ipso-C(sp2)-H bond with Carbon Dioxide: Access to Unsymmetrical Diazomalonates and Derivatives

The direct carboxylation of the ipso-C(sp2)-H bond of a diazo compound with carbon dioxide under mild reaction conditions is described. This method is transition-metal-free, uses a weak base, and proceeds at ambient temperature under atmospheric pressure in carbon dioxide. The carboxylation exhibits high reactivity and is amenable to subsequent diversification. A series of unsymmetrical 1,3-diester/keto/amide diazo compounds are obtained with moderate to excellent yields (up to 99%) with good functional group compatibility.