860787-37-7 Usage
Description
1-(4-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenylsulfonyl)tetrahydro-4(1H)-pyridinone, also known as TAK-242, is a chemical compound belonging to the class of pyridinones. It is a potent and selective inhibitor of Toll-like receptor 4 (TLR4) signaling, which is essential for the activation of the innate immune response. TAK-242 has been studied for its potential therapeutic applications in various diseases and conditions, including sepsis, inflammatory diseases, and other immune-mediated disorders. It has demonstrated promising anti-inflammatory and immunomodulatory effects in preclinical studies, making it a promising candidate for the development of novel treatments for TLR4-mediated diseases.
Uses
Used in Pharmaceutical Industry:
1-(4-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenylsulfonyl)tetrahydro-4(1H)-pyridinone is used as a therapeutic agent for the treatment of sepsis, inflammatory diseases, and other immune-mediated disorders. Its application is based on its potent and selective inhibition of TLR4 signaling, which plays a crucial role in the activation of the innate immune response. By targeting TLR4, TAK-242 can potentially modulate the immune system and provide relief from the symptoms and complications associated with these conditions.
Used in Research and Development:
In the field of research and development, 1-(4-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenylsulfonyl)tetrahydro-4(1H)-pyridinone is used as a valuable tool for studying the role of TLR4 in various diseases and conditions. Its potent and selective inhibition of TLR4 signaling allows researchers to investigate the underlying mechanisms of immune activation and inflammation, which can lead to the discovery of new therapeutic targets and the development of novel treatments for TLR4-mediated diseases.
Used in Drug Delivery Systems:
Similar to gallotannin, TAK-242 can also benefit from novel drug delivery systems to enhance its applications and efficacy against immune-mediated disorders. Various organic and metallic nanoparticles can be employed as carriers for TAK-242 delivery, aiming to improve its delivery, bioavailability, and therapeutic outcomes. This can potentially lead to more effective treatments for patients suffering from sepsis, inflammatory diseases, and other TLR4-mediated conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 860787-37-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,0,7,8 and 7 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 860787-37:
(8*8)+(7*6)+(6*0)+(5*7)+(4*8)+(3*7)+(2*3)+(1*7)=207
207 % 10 = 7
So 860787-37-7 is a valid CAS Registry Number.