86129-54-6 Usage
Description
SKF 86466 HYDROCHLORIDE is a potent and selective α2 antagonist that acts on both preand post-junctional α2-adrenoceptors.
Uses
Used in Pharmaceutical Industry:
SKF 86466 HYDROCHLORIDE is used as a research compound for studying the role of α2-adrenoceptors in various physiological processes and disorders. Its selective antagonism allows for the investigation of the specific effects of blocking these receptors, which can provide insights into potential therapeutic applications.
Used in Neurological Research:
SKF 86466 HYDROCHLORIDE is used as a tool in neurological research to understand the involvement of α2-adrenoceptors in the central nervous system. This can help in the development of treatments for neurological conditions where these receptors play a significant role.
Used in Cardiovascular Research:
SKF 86466 HYDROCHLORIDE is used as a research agent in cardiovascular studies to explore the impact of α2-adrenoceptor antagonism on heart function and blood pressure regulation. This can contribute to the advancement of therapies for cardiovascular diseases.
Used in Anesthetic Studies:
SKF 86466 HYDROCHLORIDE is used as a research tool in anesthetic studies to investigate the role of α2-adrenoceptors in the modulation of pain perception and the efficacy of anesthetic agents. This can aid in the development of improved anesthetic drugs and techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 86129-54-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,1,2 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 86129-54:
(7*8)+(6*6)+(5*1)+(4*2)+(3*9)+(2*5)+(1*4)=146
146 % 10 = 6
So 86129-54-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H14ClN.ClH/c1-13-7-5-9-3-2-4-11(12)10(9)6-8-13;/h2-4H,5-8H2,1H3;1H
86129-54-6Relevant articles and documents
PHARMACEUTICAL COMPOSITIONS AND METHODS FOR PRODUCING ALPHA ANTAGONISM
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, (2008/06/13)
Pharmaceutical compositions and methods for producing alpha. sub.2 antagonism utilize, as active ingredients, 6-halo-N-substituted 2,3, 4,5-tetrahydro-1H-3-benzazepines. These compositions are particularly useful for lowering intraocular pressure and for the treatment of abnormal cardiovascular conditions such as, for example, congestive heart failure, angina pectoris and thrombosis. The compositions and compounds of this invention, also, produce a reduction in blood pressure in hypertensive subjects and are, therefore, useful as antihypertensive agents.
Pharmaceutical compositions and method of producing alpha2 antagonism
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, (2008/06/13)
Pharmaceutical compositions and method of producing alpha2 antagonism by administering N-substituted 2,3,4,5-tetrahydro-1H-3-benzazepines.
