861369-89-3

Basic information

• Product Name: 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone
• Synonyms: 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone
• CAS NO: 861369-89-3
• Molecular Weight: 265.355
• Mol File: 861369-89-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone(861369-89-3)
• EPA Substance Registry System: 3-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylpropanone(861369-89-3)

Safety Data

• Hazardous Substances Data: 861369-89-3(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 98-86-2 acetophenone 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 936-59-4 3-chloropropiophenone 
• 4187-87-5 1-Phenyl-2-propyn-1-ol 
• 100-52-7 benzaldehyde 
• 3623-15-2 phenyl propargyl ketone 

Downstream Products

• 639467-80-4 2-(3-chloro-3-phenylpropyl)-1,2,3,4-tetrahydroisoquinoline 
• 16576-50-4 3-[3,4-dihydroisoquinolin-2(1H)-yl]-1-phenylpropan-1-ol 

Relevant articles and documents

Metal-free synthesis of β-aminoketones by the reductive hydroamination of ynones

This study describes a cascade method for the synthesis of β-aminoketones through the reductive hydroamination of alkynes under very mild metal-free conditions. It allows for the rapid conversion of ynones and amines into corresponding β-aminoketones with a broad substrate scope and diverse functionalities. This straightforward and easy-to-handle reaction process can be successfully applied for the synthesis of Proroxan and Propipocaine, offering a potential option for the synthesis of drug molecules with the β-aminoketone skeleton.