861821-64-9Relevant articles and documents
NaOH-Mediated Direct Synthesis of Quinoxalines from o-Nitroanilines and Alcohols via a Hydrogen-Transfer Strategy
Wang, Yan-Bing,Shi, Linlin,Zhang, Xiaojie,Fu, Lian-Rong,Hu, Weinan,Zhang, Wenjing,Zhu, Xinju,Hao, Xin-Qi,Song, Mao-Ping
, p. 947 - 958 (2021/01/14)
A NaOH-mediated sustainable synthesis of functionalized quinoxalines is disclosed via redox condensation of o-nitroamines with diols and α-hydroxy ketones. Under optimized conditions, various o-nitroamines and alcohols are well tolerated to generate the desired products in 44-99% yields without transition metals and external redox additives.
Synthesis of quinoxalines by a carbon nanotube-gold nanohybrid-catalyzed cascade reaction of vicinal diols and keto alcohols with diamines
Shah, Nimesh,Gravel, Edmond,Jawale, Dhanaji V.,Doris, Eric,Namboothiri, Irishi N. N.
, p. 57 - 61 (2015/03/05)
A one-pot oxidation-condensation method for the synthesis of quinoxalines from readily available benzoins or benzhydrols and 1,2-phenylenediamines or 2,3-diaminopyridine by use of a gold-carbon nanotube nanohybrid as a heterogeneous catalyst is reported. Quinoxalines are formed under mild conditions in air and in excellent yields. The simple and efficient methodology offers a safe and sustainable alternative to conventional acid and/or base-catalyzed thermal processes.
