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862135-60-2

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862135-60-2 Usage

Description

5-Bromo-2,3-dihydro-1h-inden-2-yl acetate is a chemical compound with the formula C12H13BrO2. It is an organic compound characterized by the presence of a bromine atom attached to a 2,3-dihydro-1h-inden-2-yl group, which is further connected to an acetate group. This unique structure and reactivity make it a valuable component in the synthesis of various pharmaceuticals and organic compounds. Its potential bioactive properties have been a subject of study, indicating possible applications in the development of new drugs or chemical processes. Additionally, it serves as a reagent in organic synthesis and may have other industrial applications, making it a versatile chemical compound with a broad range of uses in medicine, chemistry, and industry.

Uses

Used in Pharmaceutical Synthesis:
5-Bromo-2,3-dihydro-1h-inden-2-yl acetate is used as a key intermediate in the synthesis of various pharmaceuticals for its unique structural features and reactivity. Its presence in the molecular structure can contribute to the development of new drugs with specific therapeutic properties.
Used in Organic Synthesis:
As a reagent in organic synthesis, 5-Bromo-2,3-dihydro-1h-inden-2-yl acetate is utilized for its ability to participate in a variety of chemical reactions, facilitating the creation of complex organic compounds for research and industrial applications.
Used in Bioactive Compound Research:
5-Bromo-2,3-dihydro-1h-inden-2-yl acetate is used as a subject of study in bioactive compound research to explore its potential properties that may contribute to the development of new chemical entities with medicinal or biological significance.
Used in Chemical Process Development:
In the field of chemical process development, 5-Bromo-2,3-dihydro-1h-inden-2-yl acetate is employed to enhance or create new processes that leverage its unique chemical characteristics, potentially leading to more efficient or effective methods in chemical production.
Used in Industrial Applications:
5-Bromo-2,3-dihydro-1h-inden-2-yl acetate may also find use in various industrial applications beyond pharmaceuticals and organic synthesis, taking advantage of its chemical properties for specific technical needs or improvements in existing processes.

Check Digit Verification of cas no

The CAS Registry Mumber 862135-60-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,1,3 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 862135-60:
(8*8)+(7*6)+(6*2)+(5*1)+(4*3)+(3*5)+(2*6)+(1*0)=162
162 % 10 = 2
So 862135-60-2 is a valid CAS Registry Number.

862135-60-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-bromo-2,3-dihydro-1H-inden-2-yl) acetate

1.2 Other means of identification

Product number -
Other names 5-Bromo-2,3-dihydro-1H-inden-2-ol acetate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:862135-60-2 SDS

862135-60-2Relevant articles and documents

ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS

-

Page/Page column 220, (2008/06/13)

The present invention provides compounds of Formula (I): Formula (I) or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L1, M and R11 are as defined herein. The compounds of Formula (I) are selective inhibitors of serine protease enzymes of the coagulation cascade and/or contact activation system; for example thrombin, factor Xa, factor XIa, factor IXa, factor VIIa and/or plasma kallikrein. In particular, it relates to compounds that are selective factor XIa inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.

Concise syntheses of 2-aminoindans via indan-2-ol

G?ksu, Süleyman,Se?en, Hasan

, p. 6801 - 6807 (2007/10/03)

2-Amino-5,6-dimethoxyindan hydrochloride was synthesized in seven steps and with an overall yield of 48%. Indan-2-ol was converted to 5,6-dibromo-indan-2- ol in three steps by acetylation, electrophilic bromination and deacetylation. Dimethoxylation of 5,6-dibromoindan-2-ol with NaOCH3 in the presence of CuI gave 5,6-dimethoxy-indan-2-ol, which was converted to 2-amino-5,6-dimethoxyindan hydrochloride by azidation, followed by Pd-C catalyzed hydrogenation. Similarly, 2-amino-5-bromoindan was synthesized in five steps and with an overall yield of 50%. Indan-2-ol was converted to 2-aminoindan by azidation followed by Pd-C catalyzed hydrogenation. The reaction of 2-aminoindan with 2.5 equiv Br2 afforded 2-amino-5,6- dibromoindan.

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