86236-37-5

Basic information

• Product Name: Thieno[3,2-c]pyridine-2-carboxylic acid
• Synonyms: Thieno[3,2-c]pyridine-2-carboxylic acid
• CAS NO: 86236-37-5
• Molecular Formula: C₈H₅NO₂S
• Molecular Weight: 179.1958
• Mol File: 86236-37-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 418.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.508±0.06 g/cm3(Predicted)
• PKA: 2.48±0.30(Predicted)
• CAS DataBase Reference: Thieno[3,2-c]pyridine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[3,2-c]pyridine-2-carboxylic acid(86236-37-5)
• EPA Substance Registry System: Thieno[3,2-c]pyridine-2-carboxylic acid(86236-37-5)

Safety Data

• Hazardous Substances Data: 86236-37-5(Hazardous Substances Data)

Upstream product

• 10177-29-4 4-chloronicotinic acid 
• 189449-41-0 4-chloro-3-(hydroxymethyl)pyridine 
• 114077-82-6 4-chloronicotinaldehyde 
• 272-14-0 thieno[3,2-c]pyridine 
• 109-72-8 n-butyllithium 
• 124-38-9 carbon dioxide 
• 478149-07-4 methyl thieno[3,2-c]pyridine-2-carboxylate 

Downstream Products

• 1018953-37-1 1-(thieno[3,2-c]pyridin-2-yl)ethan-1-one 

Relevant articles and documents

NOVEL PYRAZOLE DERIVATIVE AS ALK5 INHIBITOR AND USES THEREOF

The present disclosure relates to a novel substituted pyrazole derivative having an effect of inhibiting serine/threonine kinase activity targeting receptor ALK5 of TGF-β, and a pharmaceutical composition including the compound of the present disclosure as an active ingredient may be useful in preventing and/or treating cancers, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, pulmonary diseases, cardiovascular diseases or metabolic diseases, or other diseases associated with a decrease in TGF family signaling activity.

CERTAIN TRIAZOLOPYRIDINES AND TRIAZOLOPYRAZINES, COMPOSITIONS THEREOF AND METHODS OF USE THEREFOR

Provided are certain triazolopyridines and triazolopyrazines, compositions thereof and methods of use therefor.

Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease

The invention provides compounds of Formula I: 1where in W is 2These compounds may be in the form of pharmaceutical salts or compositions, racemic mixtures, or pure enantiomers thereof. The compounds of Formula I are useful to treat diseases or conditions in which α7 is known to be involved.