86238-94-0Relevant articles and documents
Aromatic retinoic acid analogues
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, (2008/06/13)
Aromatic retinoic acid analogues of the formula STR1 where X is hydrogen or fluorine, Y is hydrogen, halogen of atomic number 9 or 17, hydroxy, alkyl of 1 to 2 carbon atoms or alkoxy of 1 to 2 carbon atoms and R is hydroxy, alkoxy, aroxy, or NR 1 R 2 where R 1 is hydrogen, alkyl, or aryl and R 2 is alkyl or aryl, with the proviso that when Y is hydrogen, X is fluorine. These retinoids are useful as chemopreventive agents for inhibiting tumor promotion in epithelial cells and for treating nonmalignant skin disorders.