862652-46-8

Basic information

• Product Name: (4-bromo-phenyl)-piperidin-4-yl-amine
• Synonyms: (4-bromo-phenyl)-piperidin-4-yl-amine
• CAS NO: 862652-46-8
• Molecular Weight: 255.157
• Mol File: 862652-46-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-bromo-phenyl)-piperidin-4-yl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromo-phenyl)-piperidin-4-yl-amine(862652-46-8)
• EPA Substance Registry System: (4-bromo-phenyl)-piperidin-4-yl-amine(862652-46-8)

Safety Data

• Hazardous Substances Data: 862652-46-8(Hazardous Substances Data)

Upstream product

• 106-40-1 4-bromo-aniline 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 443998-65-0 4-(4-Bromophenyl)amino-1-(tert-butoxycarbonyl)piperidine 

Downstream Products

• 862652-52-6 (4-bromo-phenyl)-(1-cyclopropylmethyl-piperidin-4-yl)-amine 
• 862652-48-0 (4-bromo-phenyl)-(1-cyclopentyl-piperidin-4-yl)-amine 
• 862652-50-4 (4-bromo-phenyl)-(1-ethyl-piperidin-4-yl)-amine 

Relevant articles and documents

Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists

Structural features of the substituted 4-piperidinyl urea analogs 1, responsible for the H3 antagonist activity, have been identified. Structure-activity relationship of the H3 receptor affinity, hERG ion channel inhibitory activity and their separation is described. Preliminary pharmacokinetic evaluation of the compounds of the series is addressed.