862731-12-2Relevant articles and documents
Chimeric derivatives of functionalized amino acids and α-aminoamides: Compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels
Torregrosa, Robert,Yang, Xiao-Fang,Dustrude, Erik T.,Cummins, Theodore R.,Khanna, Rajesh,Kohn, Harold
supporting information, p. 3655 - 3666 (2015/07/27)
Six novel 3″-substituted (R)-N-(phenoxybenzyl) 2-N-acetamido-3-methoxypropionamides were prepared and then assessed using whole-cell, patch-clamp electrophysiology for their anticonvulsant activities in animal seizure models and for their sodium channel a
P(i-BuNCH2CH2)3N: an efficient promoter for the microwave synthesis of diaryl ethers
Raders, Steven M.,Verkade, John G.
, p. 3507 - 3511 (2008/09/21)
With the title proazaphosphatrane as a promoter, the coupling of aryl fluorides with aryl TBDMS ethers under microwave conditions gave moderate to high yields of the desired products at low catalyst loadings and in short times. In this methodology, electron deficient aryl fluorides possessing substituents, such as nitro, cyano, and ester, were coupled with sterically demanding aryl TBDMS ethers as well as with aryl TBDMS ethers bearing a variety of functionalities such as methoxy, halo, and cyano groups.
