86282-96-4

Basic information

• Product Name: N-Tetradecanoyl-L-proline
• Synonyms: N-TETRADECANOYL-PROLINE;N-Tetradecanoyl-L-proline;1-(1-Oxotetradecyl)-L-proline;1-Tetradecanoylpyrrolidine-2-carboxylic acid
• CAS NO: 86282-96-4
• Molecular Formula: C19H35NO3
• Molecular Weight: 325.49
• Mol File: 86282-96-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 488.6 °C at 760 mmHg
• Flash Point: 249.3 °C
• Appearance: /
• Density: 1.012 g/cm³
• Refractive Index: 1.49
• CAS DataBase Reference: N-Tetradecanoyl-L-proline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Tetradecanoyl-L-proline(86282-96-4)
• EPA Substance Registry System: N-Tetradecanoyl-L-proline(86282-96-4)

Safety Data

• Hazardous Substances Data: 86282-96-4(Hazardous Substances Data)

Usage

General Description

N-Tetradecanoyl-L-proline is a chemical compound that belongs to the class of lipophilic amino acids and is derived from L-proline, an essential amino acid. It is often used in topical skincare products due to its ability to boost collagen production, promote skin hydration, and reduce the appearance of wrinkles. Additionally, N-Tetradecanoyl-L-proline has been found to possess anti-inflammatory and antioxidant properties, making it a valuable ingredient in anti-aging and rejuvenating skincare formulations. Its lipophilic nature enables it to penetrate the skin effectively, allowing for enhanced delivery of its beneficial effects. Overall, N-Tetradecanoyl-L-proline is a multifaceted chemical compound with various skincare benefits, making it a popular ingredient in cosmetic and skincare products.

InChI:InChI=1/C19H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-15-18(21)20-16-13-14-17(20)19(22)23/h17H,2-16H2,1H3,(H,22,23)/t17-/m0/s1

Upstream product

• 147-85-3 L-proline 
• 112-67-4 n-hexadecanoyl chloride 
• 112-64-1 tetradecanoyl chloride 

Relevant articles and documents

PH 7 INJECTABLE SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN OF WHICH THE PI IS FROM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS AND A LIMITED AMOUNT OF M-CRESOL

The invention relates to physically stable compositions in the form of an injectable aqueous solution, the pH of which is from 6.0 to 8.0, comprising at least: a) a basal insulin whose isoelectric point (pI) is from 5.8 to 8.5, b) m-cresol in a concentration lower than or equal to 30 mM (0 a co-polyamino acid bearing carboxylate charges and at least one Formula X hydrophobic radical.

INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS

In one embodiment, the composition according to the invention is characterized in that the co-polyamino acid bearing carboxylate charges and at least one hydrophobic radical -Hy is chosen among the co-polyamino acids according to formula XXXb hereinafter: wherein, D represents, independently, either a group —CH2— (aspartic acid) or a group —CH2—CH2— (glutamic acid),X represents a cationic entity chosen in the group comprising alkali cations,Rb and Rb′, identical or different, are either a hydrophobic radical -Hy, or a radical chosen in the group consisting of an H, a C2 to C10 linear acyl group, a C3 to C10 branched acyl group, a benzyl, a terminal “amino acid” unit and a pyroglutamate, at least one of Rb and R′b is a hydrophobic radical -Hy,Q and Hy are as defined above.n+m represents the degree of polymerization DP of the co-polyamino acid, namely the mean number of monomeric units per co-polyamino acid chain and 5≤n+m≤250.

Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid

An injectable aqueous solution, the pH of which is from 6.0 to 8.0, having at least: a) human glucagon, and b) a co-polyamino acid bearing carboxylate charges and hydrophobic radicals Hy. In an embodiment, the compositions have, in addition, a gastrointestinal hormone.