86296-02-8

Basic information

• Product Name: (3R,4S,5R)-3,4-Dimethyl-5-phenyl-2-(2-phenyl-propyl)-oxazolidine
• CAS NO: 86296-02-8
• Molecular Weight: 295.425
• Mol File: 86296-02-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (3R,4S,5R)-3,4-Dimethyl-5-phenyl-2-(2-phenyl-propyl)-oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4S,5R)-3,4-Dimethyl-5-phenyl-2-(2-phenyl-propyl)-oxazolidine(86296-02-8)
• EPA Substance Registry System: (3R,4S,5R)-3,4-Dimethyl-5-phenyl-2-(2-phenyl-propyl)-oxazolidine(86296-02-8)

Safety Data

• Hazardous Substances Data: 86296-02-8(Hazardous Substances Data)

Upstream product

• 75-16-1 methylmagnesium bromide 
• 82215-31-4 (4S,5R)-3,4-Dimethyl-5-phenyl-2-((E)-styryl)-oxazolidine 
• 82263-47-6 (2S,3R,4S,5R)-3,4-Dimethyl-5-phenyl-2-((E)-styryl)-oxazolidine 
• 917-54-4 methyllithium 

Downstream Products

• 42307-58-4 3-phenylbutanal 
• 16251-77-7 (3S)-3-phenylbutanal 
• 16251-77-7 3-Phenylbutyraldehyde 

Relevant articles and documents

ADDITION D'ORGANOCUPRATES AUX OXAZOLIDINES CHIRALES α-β ETHYLENIQUES : II -NATURE DES INTERMEDIAIRES, MECANISME ET STEREOCHIMIE

The addition of cuprates to α-β ethylenic oxazolidines leads to new organo-copper intermediate species.From the highly versatile course of the reaction it can be concluded that the first step is an unexpected 1-2 addition of the cuprate to the double bond.

ADDITION DIASTEREOSELECTIVE SUR UNE DOUBLE LIAISON EN α D'UNE OXAZOLIDINE CHIRALE

Methyl copper reacts with the 2(-)R oxazolidine (93percent optically pure) obtained from cinnamaldehyde and 1-ephedrine and leads to S(+)3-phenyl butanal with an enentiomeric excess of 35percent.