863015-71-8

Basic information

• Product Name: 3-(4-Chloro-benzoylamino)-propionic acid tert-butyl ester
• Synonyms: 3-(4-Chloro-benzoylamino)-propionic acid tert-butyl ester
• CAS NO: 863015-71-8
• Molecular Weight: 283.755
• Mol File: 863015-71-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(4-Chloro-benzoylamino)-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Chloro-benzoylamino)-propionic acid tert-butyl ester(863015-71-8)
• EPA Substance Registry System: 3-(4-Chloro-benzoylamino)-propionic acid tert-butyl ester(863015-71-8)

Safety Data

• Hazardous Substances Data: 863015-71-8(Hazardous Substances Data)

Upstream product

• 15231-41-1 tert-butyl 3-aminopropanoate 
• 122-01-0 4-chloro-benzoyl chloride 

Downstream Products

• 440341-75-3 3-[(4-chlorobenzoyl)amino]propionic acid 

Relevant articles and documents

Beta-aminoacid-derivatives as factor Xa inhibitors

The present invention relates to compounds of the formula I, in which R0 ; R1 ; R2 ; R3 ; R4; R5, R6, Q; V, G and M have the meanings indicated in the claims. The compounds of the formula I are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example, for the therapy and prophylaxis of cardiovascular disorders like thromboembolic diseases or restenoses. They are reversible inhibitors of the blood clotting enzymes factor Xa (FXa) and/or factor VIIa (FVIIa), and can in general be applied in conditions in which an undesired activity of factor Xa and/or factor VIIa is present or for the cure or prevention of which an inhibition of factor Xa and/or factor VIIa is intended. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them.