863226-76-0

Basic information

• Product Name: (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid
• Synonyms: (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid
• CAS NO: 863226-76-0
• Molecular Weight: 476.316
• Mol File: 863226-76-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid(863226-76-0)
• EPA Substance Registry System: (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid(863226-76-0)

Safety Data

• Hazardous Substances Data: 863226-76-0(Hazardous Substances Data)

Upstream product

• 863228-94-8 (S)-2-(2,6-dichloro-benzoylamino)-3-(4-boronophenyl)-propionic acid 
• 14628-57-0 4-chloro-5-methoxy-2-methyl-2H-pyridazin-3-one 
• 862854-58-8 (S)-2-amino-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid 
• 4659-45-4 2,6-Dichlorobenzoyl chloride 
• 863228-06-2 (S)-2-(2,6-Dichloro-benzoylamino)-3-[4-(5-methoxy-2-methyl-3-oxo-2,3-dihydro-pyridazin-4-yl)-phenyl]-propionic acid methyl ester 
• 76410-58-7 p-borono-L-phenylalanine 

Downstream Products

• 863227-27-4 C₂₆H₂₃Cl₂N₅O₄ 

Relevant articles and documents

Synthesis and SAR of pyridazinone-substituted phenylalanine amide α4 integrin antagonists

Structural modification and cellular adhesion inhibition activities of pyridazinone-substituted phenylalanine amide α4 integrin antagonists are described. Functionality requirements for the arylamide moiety and the carboxylic acid group were de

Pyridazinones as antagonists of alpha4 integrins

The present invention relates to certain novel compounds of Formula (I): methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of integrin mediated disorders.