86327-86-8

Basic information

• Product Name: N-(4-Chloro-phenyl)-N'-(4-oxo-3,4-dihydro-quinazolin-2-yl)-guanidine
• CAS NO: 86327-86-8
• Molecular Weight: 313.746
• Mol File: 86327-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-Chloro-phenyl)-N'-(4-oxo-3,4-dihydro-quinazolin-2-yl)-guanidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-Chloro-phenyl)-N'-(4-oxo-3,4-dihydro-quinazolin-2-yl)-guanidine(86327-86-8)
• EPA Substance Registry System: N-(4-Chloro-phenyl)-N'-(4-oxo-3,4-dihydro-quinazolin-2-yl)-guanidine(86327-86-8)

Safety Data

• Hazardous Substances Data: 86327-86-8(Hazardous Substances Data)

Upstream product

• 1482-62-8 1-(4-chlorophenyl)-3-cyanoguanidine 
• 134-20-3 2-carbomethoxyaniline 

Relevant articles and documents

Synthesis of 2-Amino- and 2-Guanidinothienopyrimidin-4(3H)-ones

Cyanamide and 1-arylcyanamides (2a-f) react with ethyl 2-aminothiophene-3-carboxylate (1a, R,R'= -(CH2)4-) to give 2-amino- and 2-arylaminothienopyrimidin-4(3H)-ones (3a-f, R''= H or Ar).A similar reaction of dicyandiamide (4a) and aryldicyandiamides (4b-f) with 1a gives 2-guanidino-thienopyrimidin-4(3H)-ones (5a-f, R''= H or Ar).However, ethyl 2-amino-4-methyl-5-(N-phenylcarboxamido)thiophene-3-carboxylate (1b, R = Me, R'= CONHPh) and ethyl 4-amino-2-imino-3-phenylthiazoline-5-carboxylate fail to give similar thieno- and thiazolo-pyrimidinones.Several new 2-(N-arylguanidino)quinazolin-4(3H)-ones (6a-e, R''= aryl) have been obtained from methyl anthranilate and aryldicyandiamides (4b-f).