863301-14-8

Basic information

• Product Name: 2-amino-2'-bromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl
• Synonyms: 2-amino-2'-bromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl
• CAS NO: 863301-14-8
• Molecular Weight: 432.338
• Mol File: 863301-14-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-amino-2'-bromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-2'-bromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl(863301-14-8)
• EPA Substance Registry System: 2-amino-2'-bromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl(863301-14-8)

Safety Data

• Hazardous Substances Data: 863301-14-8(Hazardous Substances Data)

Upstream product

• 286441-91-6 toluene-4-sulfonic acid 2-amino-5-methyl-phenyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 2835-98-5 2-Hydroxy-4-methylanilin 
• 863301-13-7 4-toluenesulfonic acid 2-amino-3-iodo-5-methylphenyl ester 
• 244205-40-1 (2-bromophenyl)boronic acid 

Downstream Products

• 863301-15-9 2,2'-dibromo-5-methyl-3-(4-toluenesulfonyloxy)-1,1'-biphenyl 

Relevant articles and documents

One-step construction of carbazoles by way of the palladium-catalyzed double N-arylation reaction and its application to the total synthesis of murrastifoline-A

The one-step construction of N-substituted carbazoles by way of the Pd-catalyzed double N-arylation reaction of primary amines with 2,2′-dibromobiphenyl is described. Aryl and aliphatic amines including tert-butylamine and a protected glucopyranosylamine were effectively transformed into the corresponding N-substituted carbazoles. The first total synthesis of murrastifoline-A, a biscarbazole alkaloid, based on this methodology is also presented.