863446-47-3

Basic information

• Product Name: 2'-O-(2-benzyloxy-2-oxoethyl)-N³-pivaloyloxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine
• CAS NO: 863446-47-3
• Molecular Weight: 749.018
• Mol File: 863446-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2'-O-(2-benzyloxy-2-oxoethyl)-N³-pivaloyloxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-(2-benzyloxy-2-oxoethyl)-N³-pivaloyloxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine(863446-47-3)
• EPA Substance Registry System: 2'-O-(2-benzyloxy-2-oxoethyl)-N³-pivaloyloxymethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine(863446-47-3)

Safety Data

• Hazardous Substances Data: 863446-47-3(Hazardous Substances Data)

Upstream product

• 69304-38-7 3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 18997-19-8 Chloromethyl pivalate 

Downstream Products

• 863446-50-8 N³-pivaloyloxymethyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-[N-(2,3-diacetoxypropyl)aminocarbonyl]methyluridine 

Relevant articles and documents

Oligonucleotides containing 2′-O-[2-(2,3-dihydroxypropyl)amino-2- oxoethyl]uridine as suitable precursors of 2′-aldehyde oligonucleotides for chemoselective ligation

2′-O-[2-(2,3-Diacetoxypropyl)amino-2-oxoethyl]uridine 3′-phosphoramidite was prepared and used in solid-phase synthesis to obtain oligonucleotides containing a 1,2-diol group, which may then be converted into a 2′-aldehyde group. The oligonucleotides were