86386-65-4

Basic information

• Product Name: 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE
• Synonyms: 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE
• CAS NO: 86386-65-4
• Molecular Formula: C₁₁H₁₀FNO₂
• Molecular Weight: 207.2010032
• Mol File: 86386-65-4.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE(86386-65-4)
• EPA Substance Registry System: 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE(86386-65-4)

Safety Data

• Hazardous Substances Data: 86386-65-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE is used as a building block for the development of new pharmaceuticals due to its potential pharmacological properties and unique structural features.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE is used as a valuable tool for research, contributing to the advancement of knowledge and understanding of organic and medicinal chemistry.
Used in Chemical Synthesis:
1-(4-FLUORO-BENZYL)-PYRROLIDINE-2,5-DIONE is employed as a key intermediate in chemical synthesis, facilitating the creation of a variety of biologically active compounds.

Upstream product

• 108-30-5 succinic acid anhydride 
• 140-75-0 para-fluorobenzylamine 
• 110-63-4 Butane-1,4-diol 
• 128-08-5 N-Bromosuccinimide 
• 352-32-9 p-fluorotoluene 
• 108-31-6 maleic anhydride 
• 123-56-8 Succinimide 
• 459-46-1 4-Fluorobenzyl bromide 

Downstream Products

• 684284-29-5 7-(4-fluoro-benzyl)-5,9-dihydroxy-pyrrolo[3,4-g]quinoline-6,8-dione 
• 915408-69-4 5-amino-7-(4-fluorobenzyl)-9-hydroxy-6H-pyrrolo[3,4-g]quinoline-6,8(7H)-dione hydrochloride 
• 1456904-97-4 C₂₄H₁₉FN₂O₄ 
• 110-63-4 Butane-1,4-diol 
• 140-75-0 para-fluorobenzylamine 
• 684286-88-2 7-(4-fluorobenzyl)-5,9-dihydroxy-pyrrolo[3,4-g]quinoxaline-6,8-dione 
• 907205-56-5 carbonic acid 5-ethoxycarbonyloxy-7-(4-fluoro-benzyl)-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester ethyl ester 
• 931402-28-7 9-benzhydryloxy-7-(4-fluoro-benzyl)-3,5-dimethoxy-pyrrolo[3,4-g]quinoline-6,8-dione 
• 907205-57-6 carbonic acid ethyl ester 7-(4-fluoro-benzyl)-5-hydroxy-3-methoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester 
• 907205-59-8 carbonic acid ethyl ester 7-(4-fluoro-benzyl)-3,5-dimethoxy-6,8-dioxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-9-yl ester 
• 871470-93-8 3-fluoro-7-(4-fluoro-benzyl)-5,9-dihydroxy-pyrrolo[3,4-g]quinoline-6,8-dione 
• 684287-01-2 1-benzyl-6-(4-fluorobenzyl)-4,8-dihydroxy-1H-1,3,6-triaza-s-indacene-5,7-dione 
• 871470-94-9 7-(4-fluoro-benzyl)-5,9-dihydroxy-3-methoxy-pyrrolo[3,4-g]quinoline-6,8-dione 

Relevant articles and documents

Preparation method of N-(aryl/heteroaryl) alkyl-diamide

The invention relates to a preparation method of N-(aryl/heteroaryl)alkyl- diamide, which comprises the following steps: under the protection of nitrogen, sequentially adding transition metal, phosphine or nitrogen ligand, cocatalyst, alkali, solvent, Nhalogenated cyclodiamide, alkyl aromatic ring or alkyl heteroaromatic ring compound into a reaction container, carrying out oxidative amination reaction at 80-140 DEG C, and till the reaction concludes after 6-48 hours, evaporating and drying a solvent and carrying out column chromatography separation to obtain an N (aryl/heteroaryl) alkyl diamide compound. The invention is simple in synthesis process, mild in reaction condition, high in yield and easy to industrialize.

Synthesis of Cyclic Imides by Acceptorless Dehydrogenative Coupling of Diols and Amines Catalyzed by a Manganese Pincer Complex

The first example of base-metal-catalyzed dehydrogenative coupling of diols and amines to form cyclic imides is reported. The reaction is catalyzed by a pincer complex of the earth abundant manganese and forms hydrogen gas as the sole byproduct, making the overall process atom economical and environmentally benign.

Porous material-immobilized iodo-Bodipy as an efficient photocatalyst for photoredox catalytic organic reaction to prepare pyrrolo[2,1-a]isoquinoline

Iodo-Bodipy immobilized on porous silica was used as an efficient recyclable photocatalyst for photoredox catalytic tandem oxidation-[3+2] cycloaddition reactions of tetrahydroisoquinoline with N-phenylmaleimides to prepare pyrrolo[2,1-a]isoquinoline.