863886-98-0

Basic information

• Product Name: 4-acetoxy-3-(2-methoxycarbonyl-propoxy-(R)-methyl)-benzoic acid methyl ester
• Synonyms: 4-acetoxy-3-(2-methoxycarbonyl-propoxy-(R)-methyl)-benzoic acid methyl ester
• CAS NO: 863886-98-0
• Molecular Weight: 324.331
• Mol File: 863886-98-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-acetoxy-3-(2-methoxycarbonyl-propoxy-(R)-methyl)-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetoxy-3-(2-methoxycarbonyl-propoxy-(R)-methyl)-benzoic acid methyl ester(863886-98-0)
• EPA Substance Registry System: 4-acetoxy-3-(2-methoxycarbonyl-propoxy-(R)-methyl)-benzoic acid methyl ester(863886-98-0)

Safety Data

• Hazardous Substances Data: 863886-98-0(Hazardous Substances Data)

Upstream product

• 42113-13-3 methyl 4-hydroxy-3-methylbenzoate 
• 499-76-3 4-hydroxy-3-methylbenzoic acid 
• 863886-93-5 4-acetoxy-3-methyl-benzoic acid methyl ester 
• 117379-88-1 4-acetoxy-3-bromomethyl-benzoic acid methyl ester 
• 72657-23-9 methyl (R)-3-hydroxy-2-methylpropionate 

Relevant articles and documents

Design and synthesis of aromatic inhibitors of anthranilate synthase

Aromatic analogues of chorismate were synthesised as potential inhibitors of anthranilate synthase. Molecular modelling using GOLD2.1 showed that these analogues docked into the active site of Serratia marcescens anthranilate synthase in the same conformation as chorismate. Most compounds were found to be micromolar inhibitors of S. marcescens anthranilate synthase. The most potent analogue, 3-(1-carboxy-ethoxy)-4-hydroxybenzoate (K1 3 μM). included a lactyl ether side chain. This appears to be a good replacement for the enol-pyruvyl side chain of chorismate. The Royal Society of Chemistry 2005.