864069-00-1 Usage
Description
2-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZONITRILE is a chemical compound that is an impurity of Imatinib (G407000), a medication used to treat certain types of cancer and diseases related to abnormal cell growth. It has gained significance as a COVID-19 related research product, indicating its potential role in the development of treatments or understanding the disease.
Used in Pharmaceutical Industry:
2-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZONITRILE is used as an impurity in Imatinib (G407000) for the treatment of cancer and diseases characterized by abnormal cell growth. Its presence in the medication is crucial for understanding the drug's efficacy and safety profile.
Used in COVID-19 Research:
2-[(4-METHYLPIPERAZIN-1-YL)METHYL]BENZONITRILE is used as a research product in the context of COVID-19. Its involvement in this area suggests that it may have potential applications in the development of treatments, vaccines, or diagnostic tools for the disease.
Check Digit Verification of cas no
The CAS Registry Mumber 864069-00-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,0,6 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 864069-00:
(8*8)+(7*6)+(6*4)+(5*0)+(4*6)+(3*9)+(2*0)+(1*0)=181
181 % 10 = 1
So 864069-00-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H17N3/c1-15-6-8-16(9-7-15)11-13-5-3-2-4-12(13)10-14/h2-5H,6-9,11H2,1H3
864069-00-1Relevant articles and documents
Aminomethylation via cyclopalladated-ferrocenylimine-complexes-catalyzed Suzuki-Miyaura coupling of aryl halides with potassium N, N - dialkylaminomethyltrifluoroborates
Zou, Dapeng,Cui, Hongmeng,Qin, Lijin,Li, Jingya,Wu, Yangjie,Wu, Yusheng
, p. 349 - 356 (2011)
Using cyclopalladated ferrocenylimine complexes (1-3 mol%) as catalysts, the Suzuki-Miyaura coupling of potassium N,N-dialkylaminomethyltrifluoroborates with aryl and heteroaryl halides were carried out in a 10:1 THF-H2O mixture at 80° in the presence of Cs2CO3 (3.0 equiv) as base, giving the desired cross-coupling products in 14-87% yields. A variety of potassium alkyltrifluoroborates were also examined. Georg Thieme Verlag Stuttgart New York.
