864130-86-9Relevant articles and documents
Asymmetric ortholithiation of amides by conformationally mediated chiral memory: An enantioselective route to naphtho- and benzofuranones
Clayden, Jonathan,Stimson, Christopher C.,Keenan, Martine
, p. 1716 - 1720 (2005)
An enantiomerically pure sulfinyl group ortho to an aromatic amide imposes absolute stereochemistry on the conformation of its Ar-CO axis. Sulfoxide-lithium exchange followed by addition to an aldehyde relays the chirality of the amide axis to the new hyd