864230-02-4

Basic information

• Product Name: 2-Fluorophenylsulphur pentafluoride
• Synonyms: 2-Fluorophenylsulphur pentafluoride;1-Fluoro-2-(pentafluorothio)benzene;2-Fluorophenylsulfur Pentafluoride;o-Fluorophenylsulfurpentafluoride
• CAS NO: 864230-02-4
• Molecular Formula: C₆H₄F₆S
• Molecular Weight: 222
• Mol File: 864230-02-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 94°C/120mmHg(lit.)
• Appearance: /
• Refractive Index: 1.4210-1.4250
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 2-Fluorophenylsulphur pentafluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluorophenylsulphur pentafluoride(864230-02-4)
• EPA Substance Registry System: 2-Fluorophenylsulphur pentafluoride(864230-02-4)

Safety Data

• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 864230-02-4(Hazardous Substances Data)

Usage

General Description

2-Fluorophenylsulphur pentafluoride, also known as 2-(pentafluorosulfanyl)fluorobenzene, is a chemical compound with the molecular formula C6H4F6S. It is a pungent-smelling, colorless liquid at room temperature and is typically used as a fluorination reagent in organic synthesis. 2-Fluorophenylsulphur pentafluoride is considered to be a highly reactive and versatile reagent in the fluorination of organic compounds, particularly in the pharmaceutical industry. It is also known for its ability to introduce fluorine atoms into organic molecules, making it an important tool for the development of new drugs and materials with improved properties. Additionally, 2-Fluorophenylsulphur pentafluoride has the potential to be used as a precursor in the synthesis of various fluorine-containing compounds.

Upstream product

• 2557-78-0 2-fluorothiophenol 
• 14135-38-7 bis(2-fluorophenyl) disulfide 
• 1062609-68-0 2-fluorophenyltetrafluoro-λ⁶-sulfanyl chloride 

Downstream Products

• 1246998-10-6 2-(pentafluoro-λ⁶-sulfanyl)aniline 

Relevant articles and documents

AgBF4-Mediated Chlorine-Fluorine Exchange Fluorination for the Synthesis of Pentafluorosulfanyl (Hetero)arenes

We report a new protocol to form pentafluorosulfanyl (hetero)arenes via chlorine-fluorine exchange of (hetero)aryl tetrafluorosulfanyl chlorides by AgBF4. The method enables access to electron-deficient pentafluorosulfanyl(hetero)arenes, which are targets that are difficult to synthesize. Two advantages of AgBF4 are its ease of handling and stability. This would be a general transformation protocol.

Generation of ortho-SF5-Benzyne and Its Diels-Alder Reactions with Furans: Synthesis of 1-SF5-Naphthalene, Its Derivatives, and 1,6(1,7)-Bis-SF5-naphthalenes

Generation of ortho-SF5-benzyne was achieved by a lithiation/elimination sequence starting from 2-fluoro-SF5-benzene. The highly reactive ortho-SF5-benzyne intermediate was trapped by furan or 2-methylfuran in situ, and th

INDUSTRIAL METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES

Industrial methods for producing arylsulfur pentafluorides are disclosed. Methods include reacting arylsulfur halotetrafluoride with hydrogen fluoride in the absence or presence of one or more additives selected from a group of fluoride salts, non-fluoride salts, and unsaturated organic compounds to form arylsulfur pentafluorides.