864269-44-3Relevant articles and documents
8-Azapurines as new inhibitors of cyclin-dependent kinases
Havlicek, Libor,Fuksova, Kveta,Krystof, Vladimir,Orsag, Martin,Vojtesek, Borivoj,Strnad, Miroslav
, p. 5399 - 5407 (2007/10/03)
Purine inhibitors of cyclin-dependent kinases (CDK) seem to be a potential anticancer drug candidate as one of the first representatives, roscovitine, is passing Phase II clinical trials for cancer and glomerulonephritis. In this article, we describe a no