864724-64-1 Usage
General Description
3-Iodo-7-nitroindazole is a chemical compound with a molecular formula of C7H4IN3O2. It is a highly potent and selective inhibitor of the enzyme nitric oxide synthase (NOS). 3-Iodo-7-nitroindazole is commonly used in research and laboratory settings to study the role of nitric oxide in various physiological and pathological processes. 3-Iodo-7-nitroindazole has been shown to have neuroprotective properties and has been utilized in studies focused on neurodegenerative diseases such as Parkinson's and Alzheimer's. Additionally, it has been investigated for its potential therapeutic applications in conditions such as ischemic stroke and inflammatory diseases. Despite its promising pharmacological properties, the safety and potential side effects of 3-Iodo-7-nitroindazole require further evaluation before it can be considered for clinical use.
Check Digit Verification of cas no
The CAS Registry Mumber 864724-64-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,4,7,2 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 864724-64:
(8*8)+(7*6)+(6*4)+(5*7)+(4*2)+(3*4)+(2*6)+(1*4)=201
201 % 10 = 1
So 864724-64-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4IN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)
864724-64-1Relevant articles and documents
Synthesis and biological evaluation of N-(7-indazolyl)benzenesulfonamide derivatives as potent cell cycle inhibitors
Bouissane,El Kazzouli,Leonce,Pfeiffer,Rakib,Khouili,Guillaumet
, p. 1078 - 1088 (2007/10/03)
We herein describe a new synthesis of N-(7-indazolyl)benzenesulfonamide derivatives. These compounds were evaluated for their antiproliferative activities toward L1210 murine leukemia cells. One of them, 4-methoxy-N-(3- chloro-7-indazolyl)benzenesulfonamide, was identified as the most potent with an IC50 of 0.44 μM.
