86474-73-9Relevant articles and documents
Preparation method of para-substituted aryl compound
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Paragraph 0530-0533, (2020/06/09)
The invention discloses a preparation method of a para-substituted aryl compound shown as a formula (I) which is described in the specfication. The preparation method is characterized by comprising the following step of: subjecting an aryl sulfonium salt shown as a formula (II) which is described in the specfication and boride to a coupling reaction in a solvent in an inert atmosphere under the action of alkali and a palladium catalyst to obtain the para-substituted aryl compound. According to the method, mono-substituted aromatic hydrocarbon is taken as a substrate, the aryl sulfonium salt isconstructed in situ, and the palladium catalyst catalyzes the aryl sulfonium salt constructed in situ to undergo the Suzuki-Miyaura coupling reaction, so a mono-substituted aromatic hydrocarbon para-arylation or alkenylation product is constructed quickly and efficiently. The method is mild in conditions, high in substrate universality and wide in tolerance of a heterocyclic coupling substrate.
Synthesis of All of the Monomethyl Isomers of Naphthothiophene
Tominaga, Yoshinori,Tedjamulia, Marvin L.,Castle, Raymond N.,Lee, Milton L.
, p. 487 - 490 (2007/10/02)
All isomers of the monomethylnaphthothiophenes were synthesized by photocyclization of 2-styrylthiophenes which were either prepared by the Wadsworth-Emmons reaction or by the condensation of 2-lithiothiophene with the corresponding carbonyl compou
