86479-06-3 Usage
Description
Hexaflumuron is a benzoylphenyl urea-type insecticide, specifically an N-acylurea, where a hydrogen attached to one of the nitrogens is replaced by a 2,6-difluorobenzoyl group, and a hydrogen attached to the other nitrogen is replaced by a 3,5-dichloro-4-(1,1,2,2-tetrafluoroethoxy)phenyl group. It is an odorless white solid or powder, typically formulated into low-concentration solid briquettes for use in bait stations. Hexaflumuron is the common name for N-(((3,5-dichloro-4-(1,1,2,2-tetrafluoro-ethoxy)phenyl)amino)carbonyl)-2,6-difluorobenzamide and is the active ingredient in several termite control products. It was the first active ingredient to be registered with the U.S. Environmental Protection Agency (EPA) as a reduced-risk pesticide, characterized by its low impact on human health, low toxicity to non-target organisms, and low potential for groundwater contamination.
Uses
Used in Pest Control Industry:
Hexaflumuron is used as an Insect Growth Regulator (IGR) for controlling various insect larvae, including those of Lepidoptera, Coleoptera, Homoptera, and Diptera on top fruit, cotton, and vegetables. It inhibits chitin synthesis, which is essential for the formation and maintenance of the exoskeleton in these insects.
Used in Forestry:
In the forestry industry, Hexaflumuron is used to protect trees and other wood structures from damage caused by termites and other wood-boring insects.
Used in Structural Pest Control:
Hexaflumuron is used as a termite pesticide for controlling subterranean termite colonies in and around buildings, fences, utility poles, decking, landscape plantings, and trees. It is used in above-ground and in-ground bait stations as part of termite monitoring and control programs. The product is designed to be regurgitated at the nest, allowing for environmentally-friendly baiting stations instead of liquid chemical barriers.
Used in Termite Baiting Systems:
Hexaflumuron is used in various termite baiting systems, such as the Sentricon? Termite Colony Elimination System, RECRUIT? AG termite bait, SHATTERtermite bait, SENTRITECH, RECRUTE? Pro, Hex-Pro(TM) Termite Baiting System, Sentricon(TM) IG Termite Bait, and Sentricon? AG Termite Bait. These systems are used by licensed pest management professionals to control and eliminate termite colonies, particularly Reticulitermes, Coptotermes, and Heterotemes species.
Hexaflumuron products are registered and sold in more than 25 countries, including Australia, Brazil, China, France, Japan, Spain, and the United States, and are used only by licensed pest management professionals. The formulations are packaged into bait stations for in-ground installation around structures and in stations for above-ground installation.
mechanism of action
Hexaflumuron is an insect growth regulator (IGR) that works by inhibiting the insect’s growth. It interferes with chitin synthesis, which termites need to form a new exoskeleton.Hexaflumuron is part of a pest monitoring system and is used selectively only in baiting stations where termite activity is present and only when the activity continues. Termites are social insects that share food and feeding sites. Foraging termites recruit nestmates to feeding sites by leaving a pheromone trail to the site, allowing the entire nest to feed on the bait containing hexaflumuron.Pest control operators use hexaflumuron as part of aboveground and underground baiting systems. They place it in a tamper-resistant bait station where foraging termites consume it.
toxicity
AnimalsHexaflumuron has a low toxicity when fed to rats in laboratory studies. See boxes on LD50,Laboratory Testing box and Toxicity Categories.Laboratory tests indicate hexaflumuron is nonirritating to the skin and eyes of rabbits.HumansScientists do not consider hexaflumuron a skin sensitizer.
reference
http://msdssearch.dow.com/PublishedLiteratureDOWCOM/dh_091b/0901b8038091b652.pdf?filepath=productsafety/pdfs/noreg/233-00932.pdf&fromPage=GetDochttp://npic.orst.edu/factsheets/hexgen.pdfhttp://www.doityourselftermitecontrol.com/chemical-termite-treatments.htmlhttps://www.caymanchem.com/product/18598http://dissemination.echa.europa.eu/Biocides/ActiveSubstances/1314-18/1314-18_Assessment_Report.pdfhttps://npic.orst.edu/factsheets/archive/hextech.pdfhttps://www.epestcontrol.com/images/Products/labels/hexaflumeroninfosheet.pdf
Potential Exposure
Hexaflumuron is a benzoyl urea insecti cide, termiticide and insect growth regulator (IGR) that inhi bits an insect’s growth through chitin synthesis, which
termites need to form an exoskeleton. It is used to impregnate
termite bait. Worldwide, there are more than 20 suppliers/
manufacturers; most are in the United States Not currently
registered for agricultural use in some EU countries.
Metabolic pathway
Although there is limited dormation on the metabolism of hexaflumuron
in the open literature, there is a useful summary provided by
Dow Agrosciences (Anon). Metabolic pathways are shown in Scheme 1.
Degradation
Hexaflumuron is stable to hydrolysis at pH 5.0 (25°C) over 33 days
and hydrolysis at pH 7.0 is slow (6% in 33 days). However, hydrolysis at
pH 9.0 was more rapid (DT50 21-23 days). Alkaline hydrolysis followed
two separate routes, namely the formation of 2,6-difluorobenzoic acid (2)
and 3,5-dichloro-4-( 1,1,2,2-tetrafluoroethoxy)phenylurea (3) and a slower
reaction to form 2,6-difluorobenzamide (4) and 3,5-dichloro-4-( 1,1,2,2-
tetrafluoroethoxy)anilhe (5).
When [14C-aniline] and [14C-benzoyl]hexaflumuron were irradiated in
sterile aqueous buffer at pH 5, the DT50 was approximately 6.3 days.
The major photolysis product from the benzoyl label was 4 (96% of the
applied radioactivity) and from the aniline label was 3,5-dichloro-4-
hydroxyaniline (6). The latter comprised 35% of the applied radioactivity
and a further 60% was released as 14CO2 from the aniline label indicating extensive ring-opening.
Incompatibilities
Decomposes in temperatures above
275 C. Irritating or toxic fumes or gases in a fire
Waste Disposal
Do not discharge into drains
or sewers. Dispose of waste material as hazardous waste
using a licensed disposal contractor to an approved land fill. Consult with environmental regulatory agencies for
guidance on acceptable disposal practices. Incineration
with effluent gas scrubbing is recommended. Containers
must be disposed of properly by following package label
directions or by contacting your local or federal environmental control agency, or by contacting your
regional EPA office.
Check Digit Verification of cas no
The CAS Registry Mumber 86479-06-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,4,7 and 9 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86479-06:
(7*8)+(6*6)+(5*4)+(4*7)+(3*9)+(2*0)+(1*6)=173
173 % 10 = 3
So 86479-06-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H8Cl2F6N2O3/c17-7-4-6(5-8(18)12(7)29-16(23,24)14(21)22)25-15(28)26-13(27)11-9(19)2-1-3-10(11)20/h1-5,14H,(H2,25,26,27,28)
86479-06-3Relevant articles and documents
Method for exterminating termites
-
, (2008/06/13)
A method for exterminating termites comprising using an entomopathogenic nematode together with an inset-growth regulator or a slow-acting insecticide, wherein insecticidal effects are reinforced compared with the cases using singly the entomopathogenic nematode and the insect-growth regulator or the slow-acting insecticide, respectively, and a bait station for exterminating termites that contains an entomopathogenic nematode with an insect-growth regulator or a slow-acting insecticide. According to the invention, emission of harmful chemicals to environment can be suppressed. The invention is nonpoisonous for human being and livestock, and is useful for indoor or outdoor extermination of termites.
1,3,4-oxadiazine derivatives and their use as pesticides
-
, (2008/06/13)
PCT No. PCT/EP97/01325 Sec. 371 Date Sep. 18, 1998 Sec. 102(e) Date Sep. 18, 1998 PCT Filed Mar. 17, 1997 PCT Pub. No. WO97/36883 PCT Pub. Date Oct. 9, 1997The invention relates to novel (1,3,4)-oxadiazine derivatives of formula (I), to a process and intermediates for their preparation, and to their usefulness as pesticides, in particular as anthelminthics, insecticides, acaricides, and nematicides.
Anti-fouling compositions
-
, (2008/06/13)
An anti-fouling composition comprising a carrier, and a binder, the improvement which comprises an effective amount of at least one insecticide. The composition is applied to the surfaces of articles which come into contact with seawater or brackish water, especially wood. Other conventional anti-fouling agents may also be present.
