86499-26-5

Basic information

• Product Name: 1H-1-Benzazepine-1-acetic acid, 3-amino-2,3,4,5-tetrahydro-2-oxo-, phenylmethyl ester
• CAS NO: 86499-26-5
• Molecular Formula: C19H20N2O3
• Molecular Weight: 324.379
• Mol File: 86499-26-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-1-Benzazepine-1-acetic acid, 3-amino-2,3,4,5-tetrahydro-2-oxo-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1-Benzazepine-1-acetic acid, 3-amino-2,3,4,5-tetrahydro-2-oxo-, phenylmethyl ester(86499-26-5)
• EPA Substance Registry System: 1H-1-Benzazepine-1-acetic acid, 3-amino-2,3,4,5-tetrahydro-2-oxo-, phenylmethyl ester(86499-26-5)

Safety Data

• Hazardous Substances Data: 86499-26-5(Hazardous Substances Data)

Upstream product

• 86499-35-6 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one 
• 5437-45-6 Benzyl bromoacetate 
• 1634-04-4 tert-butyl methyl ether 
• 497-19-8 sodium carbonate 
• 98626-45-0 1-tert-butoxycarbonylmethyl-3S-amino-2,3,4,5-tetrahydro-1H-⁽¹⁾-benzazepin-2-one 

Downstream Products

• 95384-38-6 1-benzyloxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1]-benzazepin-2,3 dione 
• 95384-39-7 1-benzyloxycarbonylmethyl-3-[5-benzyloxycarbonylamino-(1S)-1-methoxycarbonylpentylamino]-2,3,4,5-tetrahydro-1H-[1]-(3S)-benzazepin-2-one hydrochloride 

Relevant articles and documents

Pharmaceuticals which promote gastrointestinal blood circulation

The use is described of compounds of the general formula I STR1 wherein R1 represents a phenyl-lower alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or represents a naphthyl-lower alkyl group, R2 denotes hydrogen or a biolabile ester-forming group, and R3 denotes hydrogen or a biolabile ester-forming group, and physiologically acceptable salts of the acids of formula I for preparing pharmaceutical compositions for the treatment and/or prophylaxis of gastrointestinal blood circulation disturbances.

3-Amino-[1]-benzazepin-2-one-1-alkanoic acids

Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-ones and functional derivatives are angiotensin converting enzyme inhibitors and are useful as antihypertensive agents. Synthesis of, compositions and methods of treatment utilizing such compounds are included.

3-Amino-[1]-benzazepin-2-one-1-alkanoic acids

Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-ones and functional derivatives are angiotension converting enzyme inhibitors and are useful as antihypertensive agents. Synthesis of, compositions and methods of treatment utilizing such compounds are included.