865081-55-6

Basic information

• Product Name: 2-METHYL-6-(TRIFLUOROMETHYL)IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE
• Synonyms: 2-METHYL-6-(TRIFLUOROMETHYL)IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE
• CAS NO: 865081-55-6
• Molecular Formula: C8H5F3N2OS
• Molecular Weight: 234.2
• Mol File: 865081-55-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-METHYL-6-(TRIFLUOROMETHYL)IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-6-(TRIFLUOROMETHYL)IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE(865081-55-6)
• EPA Substance Registry System: 2-METHYL-6-(TRIFLUOROMETHYL)IMIDAZO[2,1-B]THIAZOLE-5-CARBALDEHYDE(865081-55-6)

Safety Data

• Hazardous Substances Data: 865081-55-6(Hazardous Substances Data)

Upstream product

• 865081-54-5 2-methyl-6-trifluoromethylimidazo[2,1-b]thiazole 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Antitumor activity of new substituted 3-(5-imidazo[2,1-b] thiazolylmethylene)-2-indolinones and study of their effect on the cell cycle

This paper reports the synthesis of a new series of 3-(5-imidazo[2,1-6] thiazolylmethylene)-2-indolinones which were tested as potential antitumor agents at the National Cancer Institute. Two derivatives are now under review by BEC (Biological Evaluation Committee of NCI). To investigate the mechanism of action, the effect on cell cycle progression was studied by monitoring them in colon adenocarcinoma HT-29: both were able to block HT-29 in mitosis. 3-[(2,6-Dimethylimidazo[2,1-b]thiazol-5-yl)methylene]-5-chloro-2-indolinone was the most active compound.