865305-34-6Relevant articles and documents
METHODS AND COMPOSITIONS FOR TREATING DISEASES AND CONDITIONS
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Paragraph 189; 192, (2016/01/25)
Provided herein include methods and compositions for treating diseases or conditions. In some embodiments provided are methods for treating one or more diseases or conditions selected from the group consisting of hypertension, heart failure, dyspnea, and
Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X3/P2X2/3 antagonist for the treatment of pain
Jahangir, Alam,Alam, Muzaffar,Carter, David S.,Dillon, Michael P.,Bois, Daisy Joe Du,Ford, Anthony P.D.W.,Gever, Joel R.,Lin, Clara,Wagner, Paul J.,Zhai, Yansheng,Zira, Jeff
scheme or table, p. 1632 - 1635 (2009/10/15)
The purinoceptor subtypes P2X3 and P2X2/3 have been shown to play a pivotal role in models of various pain conditions. Identification of a potent and selective dual P2X3/P2X2/3 diaminopyrimidine antagonist RO-4
Process for synthesis of phenoxy diaminopyrimidine derivatives
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Page/Page column 21-22, (2010/11/26)
A method for preparing a compound of formula I the method comprising treating a compound of formula d with an iodination reagent, to form the compound of formula I, wherein R1, R2 and R3 are as defined herein.