865364-83-6

Basic information

• Product Name: 4-((3-Chloro-4-fluorophenyl)amino)-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
• Synonyms: 4-((3-Chloro-4-fluorophenyl)amino)-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one
• CAS NO: 865364-83-6
• Molecular Weight: 292.7
• Mol File: 865364-83-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-((3-Chloro-4-fluorophenyl)amino)-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((3-Chloro-4-fluorophenyl)amino)-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one(865364-83-6)
• EPA Substance Registry System: 4-((3-Chloro-4-fluorophenyl)amino)-7-methyl-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one(865364-83-6)

Safety Data

• Hazardous Substances Data: 865364-83-6(Hazardous Substances Data)

Upstream product

• 39416-48-3 pyridinium hydrobromide perbromide 
• 346600-34-8 (3-chloro-4-fluoro-phenyl)-(7-methyl-7H-pyrrolo [2,3-d]pyrimidin-4-yl)-amine 
• 7781-10-4 4-Chlor-7-methyl-7H-pyrrolo<2,3-d>pyrimidin 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 3680-71-5 7-deazahypoxanthine 

Downstream Products

• 346599-93-7 5-[4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-7-METHYL-6-OXO-6,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-5-YLIDENEMETHYL]-4-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID (2-MORPHOLIN-4-YL-ETHYL)-AMIDE 
• 346600-05-3 4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-5-[3,5-DIMETHYL-4-(3-MORPHOLIN-4-YL-PROPYL)-1H-PYRROL-2-YLMETHYLENE]-7-METHYL-5,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-6-ONE 
• 346600-01-9 3-{5-[4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-7-METHYL-6-OXO-6,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-5-YLIDENEMETHYL]-2,4-DIMETHYL-1H-PYRROL-3-YL}-PROPIONIC ACID 
• 346600-03-1 3-{5-[4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-7-METHYL-6-OXO-6,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-5-YLIDENEMETHYL]-4-METHYL-1H-PYRROL-2-YL}-PROPIONIC ACID 
• 346599-95-9 4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-7-METHYL-5-[3-METHYL-5-(MORPHOLINE-4-CARBONYL)-1H-PYRROL-2-YLMETHYLENE]-5.7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-6-ONE 
• 346599-99-3 4-(3-CHLORO-4-FLUORO-PHENYLAMINO)-5-(3,5-DIMETHYL-1H-PYRROL-2-YLMETHYLENE)-7-METHYL-5,7-DIHYDRO-PYRROLO [2,3-D]PYRIMIDIN-6-ONE 

Relevant articles and documents

4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors

This invention relates to 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors. Particular 4-substituted 7-aza-indolin-2-ones disclosed herein are of Formula 1 and pharmaceutically acceptable salts, solvates, clathrates, and prodrugs thereof, wherein R1, R2, R3, R4, X, Y, and Z are defined herein. The invention fuirther relates to pharmaceutical compositions and dosage forms comprising compounds of Formula 1 and to methods of their use for the treatment and/or prevention of diseases such as, but not limited to, cancer.