86539-67-5

Basic information

• Product Name: 1-methyl-2-nitronaphtho[2,1-b]furan
• CAS NO: 86539-67-5
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227.2155
• Mol File: 86539-67-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 397.3°C at 760 mmHg
• Flash Point: 194.1°C
• Density: 1.347g/cm³
• Vapor Pressure: 3.66E-06mmHg at 25°C
• Refractive Index: 1.706
• CAS DataBase Reference: 1-methyl-2-nitronaphtho[2,1-b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-2-nitronaphtho[2,1-b]furan(86539-67-5)
• EPA Substance Registry System: 1-methyl-2-nitronaphtho[2,1-b]furan(86539-67-5)

Safety Data

• Hazardous Substances Data: 86539-67-5(Hazardous Substances Data)

Usage

Nitro-containing aromatic compound

A compound containing a nitro group (-NO2) attached to an aromatic ring, which gives it specific chemical properties and reactivity.

Common use

Organic synthesis and research This chemical is frequently used as a reactant or building block in the creation of other organic compounds, such as pharmaceuticals, dyes, and pigments.

Physical state

Yellow solid at room temperature The compound appears as a yellow solid when not melted or dissolved.

Insolubility in water

1-methyl-2-nitronaphtho[2,1-b]furan does not dissolve well in water, which can affect its handling and application in various chemical processes.

Potential hazard

Due to the presence of the nitro group, this chemical can be hazardous and should be handled with care and proper safety precautions to minimize risks of explosion, toxicity, or environmental contamination.

Upstream product

• 86539-69-7 2-acetyl-1-methylnaphtho<2,1-b>furan 

Relevant articles and documents

Research on nitro-derivatives of biological interest. XXX Methylated 2-nitronaphthofuranes, synthesis and activity against microorganisms

2-Nitrofuran derivatives methylated on their heterocycle must be prepared after various methods, according to cases. 1-Methyl 2-nitro naphtho [2. 1-b]furan is formed - with a yield of about 35% - by displacing the keton group of 2-acetyl of 2-acetyl 1-methyl naphtho [2. 1-b]furan using nitric acid in acetic acid. 7-Methoxy 1-methyl 2-nitro naphtho [2. 1-b]furan is obtained by treating 7-methoxy 1-methyl naphtho [2. 1-b]furan with a limited quantity of nitric acid in methylene chloride. Yield near to 10%. 3-Methyl 2-nitro naphtho [2. 3-b]furan is only accessible by deshydrogenation of 3-methyl 2-nitro 5.6.7.8-tetrahydro naphtho [2. 3-b]furan - which synthesis was previously described. Finally, 3-methyl 2-nitro naphtho [1. 2-b]furan is elaborated by action of nitric acid in methylene choride on 2-acetyl 3-methyl naphtho [1. 2-b]furan. Approximate yield: 25%. The methyl group added to the 2-nitro-naphthofuran heterocycle enhances the antibacterial and protozoocidal activities when one passes from 2-nitro naphtho [2. 1-b]furan to 1-methyl 2-nitro naphtho [2.1-b]furan. Nevertheless, it strongly decreases the antibacterial activity when one passes from 7-methoxy 2-nitro naphtho [2. 1-b]furan to 7-methoxy 1-methyl 2-nitro naphtho [2. 1-b]furan. The modifications in the activities noticed in the other cases are of less importance.