865626-76-2Relevant articles and documents
Carbamates as potent calcitonin gene-related peptide antagonists with improved solution stability
Degnan, Andrew P.,Conway, Charles M.,Dalterio, Richard A.,Macci, Robert,Mercer, Stephen E.,Schartman, Richard,Xu, Cen,Dubowchik, Gene M.,Macor, John E.
scheme or table, p. 3555 - 3558 (2010/03/31)
The calcitonin gene-related peptide (CGRP) receptor has been implicated in the pathogenesis of migraine. A class of urethanamide derivatives has been identified as potent inhibitors of the CGRP receptor. Compound 20 was found to be among the most potent (