866082-78-2Relevant articles and documents
Synthesis and initial evaluation of novel, non-peptidic antagonists of the αv-integrins αvβ3 and αvβ5
Letourneau, Jeffrey J.,Liu, Jinqi,Ohlmeyer, Michael H.J.,Riviello, Chris,Rong, Yajing,Li, Hong,Appell, Kenneth C.,Bansal, Shalini,Jacob, Biji,Wong, Angela,Webb, Maria L.
, p. 352 - 355 (2011/03/18)
The discovery, synthesis and preliminary SAR of a novel class of non-peptidic antagonists of the αv-integrins αvβ3 and αvβ5 is described. High-throughput screening of an extensive series of ECLiPS com
Nitrogen heterocycle biaryls for osteoporosis and other diseases
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Page/Page column 19-20; 33-35, (2010/02/14)
Nitrogen heterocycle biaryls having a carboxylate terminus are useful for treating endometriosis, osteoporosis, restenosis following angioplasty, rheumatoid arthritis, cancer, macular degeneration and obesity. Compounds of formula: are disclosed. A representative example is