86611-44-1

Basic information

• Product Name: Benzoic acid, 2-[[2-(methoxycarbonyl)phenyl]amino]-4-nitro-
• CAS NO: 86611-44-1
• Molecular Formula: C15H12N2O6
• Molecular Weight: 316.27
• Mol File: 86611-44-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[[2-(methoxycarbonyl)phenyl]amino]-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[[2-(methoxycarbonyl)phenyl]amino]-4-nitro-(86611-44-1)
• EPA Substance Registry System: Benzoic acid, 2-[[2-(methoxycarbonyl)phenyl]amino]-4-nitro-(86611-44-1)

Safety Data

• Hazardous Substances Data: 86611-44-1(Hazardous Substances Data)

Upstream product

• 610-97-9 o-iodo-methyl-benzoic acid 
• 619-17-0 4-Nitroanthranilic acid 
• 89459-38-1 4-nitro-2-iodobenzoic acid 
• 89459-39-2 5-Nitrodiphenyliodonium-2-carboxylate 
• 134-20-3 2-carbomethoxyaniline 
• 99-60-5 2-chloro-4-nitrobenzoic acid 

Downstream Products

• 86611-49-6 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-nitro-acridine-4-carboxylic acid methylamide; hydrochloride 
• 86611-48-5 9-(4-Methanesulfonylamino-2-methoxy-phenylamino)-6-nitro-acridine-4-carboxylic acid amide; hydrochloride 
• 86611-42-9 p-nitrophenyl 3-nitro-9-oxoacridan-5-carboxylate 

Relevant articles and documents

Combining G-quadruplex targeting motifs on a single peptide nucleic acid scaffold: A hybrid (3 + 1) PNA-DNA bimolecular quadruplex

We describe the first G-quadruplex targeting approach that combines intercalation and hybridization strategies by investigating the interaction of a G-rich petide nucleic acid (PNA) acridone conjugate 1 with a three-repeat fragment of the human telomere G

Acridinecarboxamide compounds

4-Carboxamidoacridine compounds represented by the general formula (I), STR1 where R1 represents H, CH3 or NHR3, where R3 is H, COCH3, SO2 CH3, COPh, SO2 Ph or lower alkyl optionally substituted with hydroxyl and/or amino functions; R2 represents H or up to two of the groups CH3, OCH3, halogen, CF3, NO2, NH2, NHCOCH3, and NHCOOCH3 placed at positions 1-3 or 5-8; Y represents C(NH)NH2, NHC(NH)NH2, or NR4 R5, where each of R4 and R5 is H or lower alkyl optionally substituted with hydroxyl and/or amino functions; and x is from 2 to 6, and the acid addition salts thereof, possess antibacterial and antitumor properties.

Potential antitumor agents. 38. 3-Substituted 5-carboxamido derivatives of amsacrine

The synthesis and biological evaluation of a series of 3-substituted 5-carboxamido derivatives of amsacrine (m-AMSA) are described. This series was developed as the result of previous quantitative structure-activity relationship (QSAR) studies of the antitumor activity of 9-anilinoacridine derivatives. In agreement with these studies, this class of compounds, possessing a variety of small nonpolar groups at the 3-position, together with very hydrophilic carboxamido groups at the 5-position, have high in vivo activity against animal leukemia models.