866211-23-6Relevant articles and documents
Structure-activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors
Mahaney, Paige E.,Kim, Callain Y.,Coghlan, Richard D.,Cohn, Stephen T.,Heffernan, Gavin D.,Huselton, Christine A.,Terefenko, Eugene A.,Vu, An T.,Zhang, Puwen,Burroughs, Kevin D.,Cosmi, Scott A.,Bray, Jenifer A.,Johnston, Grace H.,Deecher, Darlene C.,Trybulski, Eugene J.
scheme or table, p. 5807 - 5810 (2010/04/05)
The SAR of a series of 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols as monoamine reuptake inhibitors, with a goal to improve both potency toward inhibiting the norepinephrine transporter and selectivity over the serotonin transporter, is reported. The e
