866462-51-3 Usage
General Description
3-[2-(1,3-Dioxolan-2-yl)ethyl]-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one is a complex chemical compound with a unique structure. It contains a dioxolane ring, an ethyl group, and a tetrahydro-2H-3-benzazepin-2-one backbone with methoxy substituents. 3-[2-(1,3-Dioxolan-2-yl)ethyl]-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one may have potential pharmaceutical or biological applications due to its structural features, which could potentially interact with biological targets or enzymes. Further research and studies are needed to fully understand the properties and potential uses of this chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 866462-51-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,4,6 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 866462-51:
(8*8)+(7*6)+(6*6)+(5*4)+(4*6)+(3*2)+(2*5)+(1*1)=203
203 % 10 = 3
So 866462-51-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H23NO5/c1-20-14-9-12-3-5-18(6-4-17-22-7-8-23-17)16(19)11-13(12)10-15(14)21-2/h9-10,17H,3-8,11H2,1-2H3
866462-51-3Relevant articles and documents
Exploiting the Biocatalytic Toolbox for the Asymmetric Synthesis of the Heart-Rate Reducing Agent Ivabradine
Pedragosa-Moreau, Sandrine,Le Flohic, Alexandre,Thienpondt, Vivien,Lefoulon, Fran?ois,Petit, Anne-Marie,Ríos-Lombardía, Nicolás,Morís, Francisco,González-Sabín, Javier
supporting information, p. 485 - 493 (2017/02/10)
Several chemoenzymatic routes have been evaluated for the production of the heart-rate reducing agent ivabradine. Lipases and ω-transaminases have been identified as useful biocatalysts for the preparation of key enantiopure precursors. The lipase-catalysed kinetic resolution by alkoxycarbonylation of a racemic primary amine and subsequent chemical reduction of the resulting carbamate provided an N-methylated (S)-amine, one step away from ivabradine. Alternatively, the dynamic kinetic resolution by asymmetric bioamination of an aldehyde precursor enabled, in a four-step sequence, the preparative scale synthesis of enantiopure ivabradine in 50% overall yield. (Figure presented.).
