867017-31-0Relevant articles and documents
Nickel-Catalyzed Thiolation of Aryl Nitriles
Delcaillau, Tristan,Morandi, Bill
supporting information, p. 11823 - 11826 (2021/07/16)
A nickel-catalyzed thiolation of aryl nitriles has been developed to access functionalized aryl thioethers. The ligand dcype (1,2-bis(dicyclohexylphosphino)ethane) as well as the base KOtBu (potassium tert-butoxide) are essential to achieve this transformation. This scalable and practical process involves both a C?C bond activation and a C?S bond formation. Furthermore, this reaction shows a high functional-group tolerance and enables the late-stage functionalization of important molecules.
CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION
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Page/Page column 9; 16; 17, (2018/09/28)
The present invention refers to a process for a catalytic aryl transfer to rearrange the backbone of aromatic C-X bonds.
Microwave-Assisted Copper-Catalyzed Cross-Coupling Reaction of Thiols with Aryl Iodides in Water
Chen, Yi-An,Badsara, Satpal Singh,Tsai, Wan-Ting,Lee, Chin-Fa
, p. 181 - 186 (2015/05/04)
Microwave-promoted C-S bond formation from thiols and aryl iodides in the presence of a copper catalyst is reported. A combination of copper(II) oxide and 1,10-phenanthroline catalyzes this reaction. A variety of aryl iodides react smoothly with thiols to provide the corresponding aryl sulfides in good to excellent yields. Notably, the reactions proceed in water with a short reaction time (30 minutes). This system shows broad functional-group tolerance; amino, chloro, bromo, acetyl, and nitro groups are unaffected by the reaction conditions.